Component

Citrus pectin, preparation specified by study

Citrus pectin, preparation specified by study. Species, exposure and limitations are retained in each linked claim.

14 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. The beta-carotene plasma rise was smaller at 30 and 192 hours after the pectin meal; the 30-hour rise was reduced by more than half.

    Citrus pectin, preparation specified by study → Human post-meal plasma beta-carotene response source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/1309477.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7", "start_char": 0, "end_char": 1044, "text_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7"}
    experimental_model
    Crossover meal study in seven participants
    exposure
    12 g citrus pectin with 25 mg beta-carotene and a 500-kcal meal
    limitations
    Plasma response is an absorption-related endpoint, not a direct vitamin A deficiency measurement.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The meal experiment found less beta-carotene appearing in blood.
    primary_references
    [pectin-p1309477] Plasma beta-carotene response in humans after meals supplemented with dietary pectin. (1992). https://pubmed.ncbi.nlm.nih.gov/1309477/ DOI: 10.1093/ajcn/55.1.96
    tissue_or_cell_type
    Post-meal plasma

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 659–670

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Crossover meal study in seven participants · source_derived_draft · unverified_draft

    ### pectin-beta-carotene-meal The beta-carotene plasma rise was smaller at 30 and 192 hours after the pectin meal; the 30-hour rise was reduced by more than half. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The meal experiment found less beta-carotene appearing in blood. organism: Homo sapiens tissue_or_cell_type: Post-meal plasma experimental_model: Crossover meal study in seven participants limitations: Plasma response is an absorption-related endpoint, not a direct vitamin A deficiency measurement. exposure: 12 g citrus pectin with 25 mg beta-carotene and a 500-kcal meal evidence_span: {"source_cache": "artifacts/pectin-research/1309477.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7", "start_char": 0, "end_char": 1044, "text_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7"} [pectin-p1309477] Plasma beta-carotene response in humans after meals supplemented with dietary pectin. (1992). https://pubmed.ncbi.nlm.nih.gov/1309477/ DOI: 10.1093/ajcn/55.1.96
    Complete structured claim and evidence

  2. Calcium binding also increased with the tested structural changes.

    Citrus pectin, preparation specified by study → Calcium ion source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"}
    experimental_model
    Adsorption isotherms and simulated digestion
    exposure
    Citrus pectin with varied methylesterification and blockiness
    limitations
    In-vitro accessibility is not human mineral status.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    No organism; in-vitro food chemistry
    plain_language
    Calcium interacts with the polymer.
    primary_references
    [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    tissue_or_cell_type
    Pectin-mineral solutions

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 503–514

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Adsorption isotherms and simulated digestion · source_derived_draft · unverified_draft

    ### pectin-calcium-binding Calcium binding also increased with the tested structural changes. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Calcium interacts with the polymer. organism: No organism; in-vitro food chemistry tissue_or_cell_type: Pectin-mineral solutions experimental_model: Adsorption isotherms and simulated digestion limitations: In-vitro accessibility is not human mineral status. exposure: Citrus pectin with varied methylesterification and blockiness evidence_span: {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"} [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    Complete structured claim and evidence

  3. Apparent calcium absorption was unchanged in the ileostomy study.

    Citrus pectin, preparation specified by study → Intestinal calcium absorption source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The effect on iron did not extend to every mineral.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 607–618

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-calcium-null Apparent calcium absorption was unchanged in the ileostomy study. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The effect on iron did not extend to every mineral. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  4. Pectin increased ileal fat output.

    Citrus pectin, preparation specified by study → Human ileal fat output source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    More dietary fat reached the collection bag.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 581–592

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-fat Pectin increased ileal fat output. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: More dietary fat reached the collection bag. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  5. Apparent iron absorption fell in this ileostomy experiment.

    Citrus pectin, preparation specified by study → Nonheme iron absorption source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    Less iron disappeared before the end of the small intestine.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 542–553

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-iron Apparent iron absorption fell in this ileostomy experiment. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Less iron disappeared before the end of the small intestine. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  6. Pectin increased ileal nitrogen output.

    Citrus pectin, preparation specified by study → Human ileal nitrogen output source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    More nitrogen-containing material was recovered; this is not a diagnosis of protein deficiency.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 594–605

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-nitrogen Pectin increased ileal nitrogen output. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: More nitrogen-containing material was recovered; this is not a diagnosis of protein deficiency. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  7. Pectin increased potassium output in ileal effluent.

    Citrus pectin, preparation specified by study → Human ileal potassium output source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The potassium finding belongs to people with an ileostomy in this study.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 568–579

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-potassium Pectin increased potassium output in ileal effluent. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The potassium finding belongs to people with an ileostomy in this study. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  8. Approximately 70-100% of added uronic acids were recovered at the ileostomy.

    Citrus pectin, preparation specified by study → Pectin-derived uronic acids recovered in ileal effluent source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    Much of this pectin passed through the small intestine.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 529–540

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-recovery Approximately 70-100% of added uronic acids were recovered at the ileostomy. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Much of this pectin passed through the small intestine. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  9. Pectin increased sodium output in ileal effluent.

    Citrus pectin, preparation specified by study → Human ileal sodium output source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    More sodium left through the ileostomy; this is not proof of low blood sodium.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 555–566

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-sodium Pectin increased sodium output in ileal effluent. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: More sodium left through the ileostomy; this is not proof of low blood sodium. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  10. Apparent zinc absorption was unchanged in this study.

    Citrus pectin, preparation specified by study → Intestinal zinc absorption source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"}
    experimental_model
    Within-person ileostomy balance study; six participants
    exposure
    15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol
    limitations
    Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    An in-vitro zinc-binding result cannot simply be substituted for a human absorption result.
    primary_references
    [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    tissue_or_cell_type
    Small intestine; ileal effluent

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 620–631

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Within-person ileostomy balance study; six participants · source_derived_draft · unverified_draft

    ### pectin-ileal-zinc-null Apparent zinc absorption was unchanged in this study. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: An in-vitro zinc-binding result cannot simply be substituted for a human absorption result. organism: Homo sapiens tissue_or_cell_type: Small intestine; ileal effluent experimental_model: Within-person ileostomy balance study; six participants limitations: Ileal apparent absorption and output are not whole-body status or clinical deficiency; the colon was bypassed. exposure: 15 g/day citrus pectin on days 5-7 of a 10-day low-fiber feeding protocol evidence_span: {"source_cache": "artifacts/pectin-research/6307932.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1", "start_char": 0, "end_char": 1593, "text_sha256": "fd45607a7ff1d1a20dd52d145134da591847919c3db47ef8a8cf5693fb9f80a1"} [pectin-p6307932] The effect of citrus pectin on the absorption of nutrients in the small intestine. (1983). https://pubmed.ncbi.nlm.nih.gov/6307932/
    Complete structured claim and evidence

  11. Citrus DE70 pectin reduced LDL by approximately 7-10% in the 15-g/day comparison, outperforming several other preparations.

    Citrus pectin, preparation specified by study → LDL cholesterol concentration source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/22190137.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611", "start_char": 0, "end_char": 1601, "text_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611"}
    experimental_model
    Randomized crossover comparisons of pectin preparations
    exposure
    15 g/day for four weeks; additional high-MW citrus preparation at 6 g/day for three weeks; cellulose comparator
    limitations
    Preparation-specific lipid surrogates; no cardiovascular event outcome. Methylesterification alone did not explain every preparation difference.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The pectin preparation influenced the cholesterol result.
    primary_references
    [pectin-p22190137] Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. (2012). https://pubmed.ncbi.nlm.nih.gov/22190137/ DOI: 10.1038/ejcn.2011.208
    tissue_or_cell_type
    Circulating lipids

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 763–774

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized crossover comparisons of pectin preparations · source_derived_draft · unverified_draft

    ### pectin-ldl-citrus Citrus DE70 pectin reduced LDL by approximately 7-10% in the 15-g/day comparison, outperforming several other preparations. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The pectin preparation influenced the cholesterol result. organism: Homo sapiens tissue_or_cell_type: Circulating lipids experimental_model: Randomized crossover comparisons of pectin preparations limitations: Preparation-specific lipid surrogates; no cardiovascular event outcome. Methylesterification alone did not explain every preparation difference. exposure: 15 g/day for four weeks; additional high-MW citrus preparation at 6 g/day for three weeks; cellulose comparator evidence_span: {"source_cache": "artifacts/pectin-research/22190137.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611", "start_char": 0, "end_char": 1601, "text_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611"} [pectin-p22190137] Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. (2012). https://pubmed.ncbi.nlm.nih.gov/22190137/ DOI: 10.1038/ejcn.2011.208
    Complete structured claim and evidence

  12. The tested high-molecular-weight DE70 citrus pectins at 6 g/day lowered LDL by approximately 6-7%.

    Citrus pectin, preparation specified by study → LDL cholesterol concentration source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/22190137.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611", "start_char": 0, "end_char": 1601, "text_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611"}
    experimental_model
    Randomized crossover comparisons of pectin preparations
    exposure
    15 g/day for four weeks; additional high-MW citrus preparation at 6 g/day for three weeks; cellulose comparator
    limitations
    Preparation-specific lipid surrogates; no cardiovascular event outcome. Methylesterification alone did not explain every preparation difference.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The trial also found an LDL response at its lower tested regimen.
    primary_references
    [pectin-p22190137] Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. (2012). https://pubmed.ncbi.nlm.nih.gov/22190137/ DOI: 10.1038/ejcn.2011.208
    tissue_or_cell_type
    Circulating lipids

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 789–800

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized crossover comparisons of pectin preparations · source_derived_draft · unverified_draft

    ### pectin-ldl-low-dose The tested high-molecular-weight DE70 citrus pectins at 6 g/day lowered LDL by approximately 6-7%. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The trial also found an LDL response at its lower tested regimen. organism: Homo sapiens tissue_or_cell_type: Circulating lipids experimental_model: Randomized crossover comparisons of pectin preparations limitations: Preparation-specific lipid surrogates; no cardiovascular event outcome. Methylesterification alone did not explain every preparation difference. exposure: 15 g/day for four weeks; additional high-MW citrus preparation at 6 g/day for three weeks; cellulose comparator evidence_span: {"source_cache": "artifacts/pectin-research/22190137.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611", "start_char": 0, "end_char": 1601, "text_sha256": "20212c2dcb0b2018c37d0eac06932c1ec9da0a9d514bb3bd905f476594b32611"} [pectin-p22190137] Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. (2012). https://pubmed.ncbi.nlm.nih.gov/22190137/ DOI: 10.1038/ejcn.2011.208
    Complete structured claim and evidence

  13. Stronger zinc binding accompanied lower simulated-digestion bioaccessibility.

    Citrus pectin, preparation specified by study → Zinc bioaccessibility in simulated digestion source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"}
    experimental_model
    Adsorption isotherms and simulated digestion
    exposure
    Citrus pectin with varied methylesterification and blockiness
    limitations
    In-vitro accessibility is not human mineral status.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    No organism; in-vitro food chemistry
    plain_language
    Laboratory accessibility can fall.
    primary_references
    [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    tissue_or_cell_type
    Pectin-mineral solutions

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 516–527

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Adsorption isotherms and simulated digestion · source_derived_draft · unverified_draft

    ### pectin-zinc-accessibility Stronger zinc binding accompanied lower simulated-digestion bioaccessibility. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Laboratory accessibility can fall. organism: No organism; in-vitro food chemistry tissue_or_cell_type: Pectin-mineral solutions experimental_model: Adsorption isotherms and simulated digestion limitations: In-vitro accessibility is not human mineral status. exposure: Citrus pectin with varied methylesterification and blockiness evidence_span: {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"} [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    Complete structured claim and evidence

  14. Lower methylesterification and greater blockiness favored zinc binding.

    Citrus pectin, preparation specified by study → Zinc source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"}
    experimental_model
    Adsorption isotherms and simulated digestion
    exposure
    Citrus pectin with varied methylesterification and blockiness
    limitations
    In-vitro accessibility is not human mineral status.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    No organism; in-vitro food chemistry
    plain_language
    Pectin structure changes mineral binding.
    primary_references
    [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    tissue_or_cell_type
    Pectin-mineral solutions

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 490–501

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Adsorption isotherms and simulated digestion · source_derived_draft · unverified_draft

    ### pectin-zinc-binding Lower methylesterification and greater blockiness favored zinc binding. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Pectin structure changes mineral binding. organism: No organism; in-vitro food chemistry tissue_or_cell_type: Pectin-mineral solutions experimental_model: Adsorption isotherms and simulated digestion limitations: In-vitro accessibility is not human mineral status. exposure: Citrus pectin with varied methylesterification and blockiness evidence_span: {"source_cache": "artifacts/pectin-research/celus2018.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472", "start_char": 0, "end_char": 1681, "text_sha256": "2ac4b4f67d7dfb4d68a06455691f949be93304d25c3475bd8caf4d618d96f472"} [pectin-pcelus2018] Interactions between citrus pectin and Zn2+ or Ca2+ and associated in vitro Zn2+ bioaccessibility as affected by degree of methylesterification and blockiness (2018). https://doi.org/10.1016/j.foodhyd.2018.01.003 DOI: 10.1016/j.foodhyd.2018.01.003
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards