Component

Human post-meal plasma beta-carotene response

Human post-meal plasma beta-carotene response. Species, exposure and limitations are retained in each linked claim.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Adding lutein reduced the postprandial beta-carotene response, more strongly when lutein predominated.

    Lutein → Human post-meal plasma beta-carotene response source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/lutein-research/9857262.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "22d6d633851b14b6c170fecfb2b3ef493c263f1640d690a2ee3a1d3bf9ccc77f", "start_char": 0, "end_char": 892, "text_sha256": "22d6d633851b14b6c170fecfb2b3ef493c263f1640d690a2ee3a1d3bf9ccc77f"}
    experimental_model
    Original single-meal volunteer data reported alongside a literature discussion
    exposure
    Beta-carotene alone or combined with lutein; beta-carotene:lutein ratios 2:1 and 1:2
    limitations
    Record uses the original experiment, not the review portion; reduced uptake did not imply impaired cleavage of absorbed beta-carotene.
    nutrient_topic
    Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
    organism
    Human volunteers
    plain_language
    The ratio of carotenoids mattered in the test meal.
    primary_references
    [lutein-p9857262] Effect of lutein on beta-carotene absorption and cleavage. (1998). https://pubmed.ncbi.nlm.nih.gov/9857262/
    tissue_or_cell_type
    Postprandial triglyceride-rich lipoproteins

    Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 554–565

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Original single-meal volunteer data reported alongside a literature discussion · source_derived_draft · unverified_draft

    ### lutein-human-beta-absorption Adding lutein reduced the postprandial beta-carotene response, more strongly when lutein predominated. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: The ratio of carotenoids mattered in the test meal. organism: Human volunteers tissue_or_cell_type: Postprandial triglyceride-rich lipoproteins experimental_model: Original single-meal volunteer data reported alongside a literature discussion limitations: Record uses the original experiment, not the review portion; reduced uptake did not imply impaired cleavage of absorbed beta-carotene. exposure: Beta-carotene alone or combined with lutein; beta-carotene:lutein ratios 2:1 and 1:2 evidence_span: {"source_cache": "artifacts/lutein-research/9857262.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "22d6d633851b14b6c170fecfb2b3ef493c263f1640d690a2ee3a1d3bf9ccc77f", "start_char": 0, "end_char": 892, "text_sha256": "22d6d633851b14b6c170fecfb2b3ef493c263f1640d690a2ee3a1d3bf9ccc77f"} [lutein-p9857262] Effect of lutein on beta-carotene absorption and cleavage. (1998). https://pubmed.ncbi.nlm.nih.gov/9857262/
    Complete structured claim and evidence

  2. The beta-carotene plasma rise was smaller at 30 and 192 hours after the pectin meal; the 30-hour rise was reduced by more than half.

    Citrus pectin, preparation specified by study → Human post-meal plasma beta-carotene response source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/1309477.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7", "start_char": 0, "end_char": 1044, "text_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7"}
    experimental_model
    Crossover meal study in seven participants
    exposure
    12 g citrus pectin with 25 mg beta-carotene and a 500-kcal meal
    limitations
    Plasma response is an absorption-related endpoint, not a direct vitamin A deficiency measurement.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    The meal experiment found less beta-carotene appearing in blood.
    primary_references
    [pectin-p1309477] Plasma beta-carotene response in humans after meals supplemented with dietary pectin. (1992). https://pubmed.ncbi.nlm.nih.gov/1309477/ DOI: 10.1093/ajcn/55.1.96
    tissue_or_cell_type
    Post-meal plasma

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 659–670

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Crossover meal study in seven participants · source_derived_draft · unverified_draft

    ### pectin-beta-carotene-meal The beta-carotene plasma rise was smaller at 30 and 192 hours after the pectin meal; the 30-hour rise was reduced by more than half. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The meal experiment found less beta-carotene appearing in blood. organism: Homo sapiens tissue_or_cell_type: Post-meal plasma experimental_model: Crossover meal study in seven participants limitations: Plasma response is an absorption-related endpoint, not a direct vitamin A deficiency measurement. exposure: 12 g citrus pectin with 25 mg beta-carotene and a 500-kcal meal evidence_span: {"source_cache": "artifacts/pectin-research/1309477.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7", "start_char": 0, "end_char": 1044, "text_sha256": "fd0dad35ab4b3d100f22763fd9f5493d4ee5cc4e36f6f959436157484bd3f2f7"} [pectin-p1309477] Plasma beta-carotene response in humans after meals supplemented with dietary pectin. (1992). https://pubmed.ncbi.nlm.nih.gov/1309477/ DOI: 10.1093/ajcn/55.1.96
    Complete structured claim and evidence

  3. Pectin was among soluble fibers that lowered beta-carotene AUC; the 33-43% range covered the soluble fibers tested.

    Pectin, structurally heterogeneous plant polysaccharides → Human post-meal plasma beta-carotene response source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/10573545.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332", "start_char": 0, "end_char": 1340, "text_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332"}
    experimental_model
    Crossover mixed-carotenoid meal study in six healthy women
    exposure
    Pectin or other fibers at 0.15 g/kg with a carotenoid and alpha-tocopherol mixture
    limitations
    Reported effect-size ranges cover multiple fibers, not one pectin-specific estimate. Plasma exposure does not establish long-term deficiency.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Homo sapiens
    plain_language
    Fiber type affected beta-carotene exposure.
    primary_references
    [pectin-p10573545] Some dietary fibers reduce the absorption of carotenoids in women. (1999). https://pubmed.ncbi.nlm.nih.gov/10573545/ DOI: 10.1093/jn/129.12.2170
    tissue_or_cell_type
    Plasma 24-hour area under the curve

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 672–683

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Crossover mixed-carotenoid meal study in six healthy women · source_derived_draft · unverified_draft

    ### pectin-carotene-auc Pectin was among soluble fibers that lowered beta-carotene AUC; the 33-43% range covered the soluble fibers tested. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Fiber type affected beta-carotene exposure. organism: Homo sapiens tissue_or_cell_type: Plasma 24-hour area under the curve experimental_model: Crossover mixed-carotenoid meal study in six healthy women limitations: Reported effect-size ranges cover multiple fibers, not one pectin-specific estimate. Plasma exposure does not establish long-term deficiency. exposure: Pectin or other fibers at 0.15 g/kg with a carotenoid and alpha-tocopherol mixture evidence_span: {"source_cache": "artifacts/pectin-research/10573545.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332", "start_char": 0, "end_char": 1340, "text_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332"} [pectin-p10573545] Some dietary fibers reduce the absorption of carotenoids in women. (1999). https://pubmed.ncbi.nlm.nih.gov/10573545/ DOI: 10.1093/jn/129.12.2170
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards