Component

trans-11 vaccenic acid

Context-specific entity; species, compartment and exposure are stated on each claim.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Feeding increasing vaccenic-acid intakes gave an estimated mean conversion to rumenic acid of 19%, with substantial individual variation.

    trans-11 vaccenic acid → cis-9,trans-11 conjugated linoleic acid / rumenic acid source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Thirty healthy adults; 1.5, 3 or 4.5 g/day vaccenic acid for nine days.
    limitations
    Protocol-specific estimate; not an instruction to consume these amounts.
    nutrient_topic
    CLA collection; isomer, preparation, species, exposure and manipulation remain explicit. · Conjugated linoleic acid / CLA isomer family
    plain_language
    Food-derived precursor supply contributes to measured CLA.
    primary_references
    Bioconversion of vaccenic acid to conjugated linoleic acid in humans. · 2002 · https://pubmed.ncbi.nlm.nih.gov/12197992/ · DOI 10.1093/ajcn/76.3.504

    Conjugated linoleic acid: isomers, signaling, nutrient interactions and discovery (2026-09-19) · lines 30–36

    AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Thirty healthy adults; 1.5, 3 or 4.5 g/day vaccenic acid for nine days. · source_derived_draft · unverified_draft

    ## cla-conversion-rate Food-derived precursor supply contributes to measured CLA. Feeding increasing vaccenic-acid intakes gave an estimated mean conversion to rumenic acid of 19%, with substantial individual variation. Model: Thirty healthy adults; 1.5, 3 or 4.5 g/day vaccenic acid for nine days. Limitations: Protocol-specific estimate; not an instruction to consume these amounts. Evidence access: Primary abstract Bioconversion of vaccenic acid to conjugated linoleic acid in humans. · 2002 · https://pubmed.ncbi.nlm.nih.gov/12197992/ · DOI 10.1093/ajcn/76.3.504
    Complete structured claim and evidence

  2. Deuterated trans-vaccenic acid administered as triglyceride produced labeled cis-9,trans-11 CLA in human serum lipids.

    trans-11 vaccenic acid → cis-9,trans-11 conjugated linoleic acid / rumenic acid source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Reanalysis of four historical single-person tracer experiments.
    limitations
    Small tracer evidence; enrichment is not a universal dietary conversion fraction.
    nutrient_topic
    CLA collection; isomer, preparation, species, exposure and manipulation remain explicit. · Conjugated linoleic acid / CLA isomer family
    plain_language
    The body can make one CLA isomer from a distinct dietary precursor.
    primary_references
    Biosynthesis of conjugated linoleic acid in humans. · 2000 · https://pubmed.ncbi.nlm.nih.gov/10757542/ · DOI 10.1007/BF02664761

    Conjugated linoleic acid: isomers, signaling, nutrient interactions and discovery (2026-09-19) · lines 22–28

    AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Reanalysis of four historical single-person tracer experiments. · source_derived_draft · unverified_draft

    ## cla-vaccenic-tracer The body can make one CLA isomer from a distinct dietary precursor. Deuterated trans-vaccenic acid administered as triglyceride produced labeled cis-9,trans-11 CLA in human serum lipids. Model: Reanalysis of four historical single-person tracer experiments. Limitations: Small tracer evidence; enrichment is not a universal dietary conversion fraction. Evidence access: Primary abstract Biosynthesis of conjugated linoleic acid in humans. · 2000 · https://pubmed.ncbi.nlm.nih.gov/10757542/ · DOI 10.1007/BF02664761
    Complete structured claim and evidence

Where it participates (unsigned role)

  1. Enriched dairy increased c9,t11 CLA in plasma phosphatidylcholine, triglycerides, cholesteryl esters and peripheral blood mononuclear cells.

    cis-9,trans-11 conjugated linoleic acid / rumenic acid → Human CLA incorporation into plasma and leukocyte lipids source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Double-blind crossover in healthy men; enriched products supplied both CLA and vaccenic acid for six weeks.
    limitations
    Cannot separate direct CLA intake from precursor conversion or infer health benefit.
    nutrient_topic
    CLA collection; isomer, preparation, species, exposure and manipulation remain explicit. · Conjugated linoleic acid / CLA isomer family
    plain_language
    CLA reached several lipid compartments.
    primary_references
    Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18 : 1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids. · 2005 · https://pubmed.ncbi.nlm.nih.gov/16115358/ · DOI 10.1079/bjn20051506

    Conjugated linoleic acid: isomers, signaling, nutrient interactions and discovery (2026-09-19) · lines 38–44

    AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Double-blind crossover in healthy men; enriched products supplied both CLA and vaccenic acid for six weeks. · source_derived_draft · unverified_draft

    ## cla-incorporation CLA reached several lipid compartments. Enriched dairy increased c9,t11 CLA in plasma phosphatidylcholine, triglycerides, cholesteryl esters and peripheral blood mononuclear cells. Model: Double-blind crossover in healthy men; enriched products supplied both CLA and vaccenic acid for six weeks. Limitations: Cannot separate direct CLA intake from precursor conversion or infer health benefit. Evidence access: Primary abstract Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18 : 1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids. · 2005 · https://pubmed.ncbi.nlm.nih.gov/16115358/ · DOI 10.1079/bjn20051506
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards