Component

Rose bengal

Study-specific endpoint; inspect claim context for model and measurement.

5 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

Where it participates (unsigned role)

  1. Illuminated Rose bengal plus KI generated free iodine detected with starch.

    Potassium iodide → Molecular iodine (I2) source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    Illumination converted iodide into reactive iodine.
    primary_references
    Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 320–326

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft

    ## ki-pdt-iodine Illumination converted iodide into reactive iodine. Illuminated Rose bengal plus KI generated free iodine detected with starch. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Full-text mechanistic results, Figure 4A Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
    Complete structured claim and evidence

  2. KI increased light/Rose-bengal killing by up to six logs in the tested bacterial and Candida systems.

    Potassium iodide → Microbial viability in the specified assay source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    KI amplified an externally activated antimicrobial reaction.
    primary_references
    Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 312–318

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft

    ## ki-pdt-killing KI amplified an externally activated antimicrobial reaction. KI increased light/Rose-bengal killing by up to six logs in the tested bacterial and Candida systems. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Primary abstract Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
    Complete structured claim and evidence

  3. KI potentiated Rose-bengal photodynamic treatment in Pseudomonas-infected mouse skin abrasions.

    Potassium iodide → Pseudomonas wound infection in mice source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The combination was also tested in a local animal infection.
    primary_references
    Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 344–350

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft

    ## ki-pdt-mouse The combination was also tested in a local animal infection. KI potentiated Rose-bengal photodynamic treatment in Pseudomonas-infected mouse skin abrasions. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Primary abstract Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
    Complete structured claim and evidence

  4. The illuminated mixture generated peroxide measured by Amplex Red.

    Potassium iodide → Hydrogen peroxide source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    This reaction produced peroxide rather than universally removing it.
    primary_references
    Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 328–334

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft

    ## ki-pdt-peroxide This reaction produced peroxide rather than universally removing it. The illuminated mixture generated peroxide measured by Amplex Red. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Full-text Figure 4B Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
    Complete structured claim and evidence

  5. KI shortened singlet-oxygen lifetime; derived quenching rate was 1.1 × 10^6 M−1 s−1.

    Iodide ion → Singlet molecular oxygen source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    Iodide intercepted singlet oxygen in the photochemical system.
    primary_references
    Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 336–342

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft

    ## ki-pdt-singlet Iodide intercepted singlet oxygen in the photochemical system. KI shortened singlet-oxygen lifetime; derived quenching rate was 1.1 × 10^6 M−1 s−1. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Full-text Figure 5 Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards