Component
Molecular iodine (I2)
Study-specific endpoint; inspect claim context for model and measurement.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Molecular iodine oxidized NADH without enzyme and was proposed as an intermediate of iodide-dependent oxidation.
Experimental context and source evidence
- experimental_model
- Cell-free LPO/H2O2 reactions with nicotinamide nucleotides.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Chemical oxidation is not evidence that supplementation drains niacin in vivo; the authors expected thiocyanate oxidation to predominate in milk/saliva.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- Oxidized iodine can carry the reaction onward.
- primary_references
- The oxidation of reduced nicotinamide nucleotides by hydrogen peroside in the presence of lactoperoxidase and thiocyanate, iodide or bromide. · 1970 · https://pubmed.ncbi.nlm.nih.gov/4317722/ · DOI 10.1042/bj1170791
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 272–278
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Cell-free LPO/H2O2 reactions with nicotinamide nucleotides. · source_derived_draft · unverified_draft
## ki-iodine-nadh Oxidized iodine can carry the reaction onward. Molecular iodine oxidized NADH without enzyme and was proposed as an intermediate of iodide-dependent oxidation. Model: Cell-free LPO/H2O2 reactions with nicotinamide nucleotides. Limitations: Chemical oxidation is not evidence that supplementation drains niacin in vivo; the authors expected thiocyanate oxidation to predominate in milk/saliva. Evidence location: Primary abstract The oxidation of reduced nicotinamide nucleotides by hydrogen peroside in the presence of lactoperoxidase and thiocyanate, iodide or bromide. · 1970 · https://pubmed.ncbi.nlm.nih.gov/4317722/ · DOI 10.1042/bj1170791
Complete structured claim and evidence
What acts on it
Illuminated Rose bengal plus KI generated free iodine detected with starch.
Experimental context and source evidence
- experimental_model
- Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- Illumination converted iodide into reactive iodine.
- primary_references
- Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 320–326
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. · source_derived_draft · unverified_draft
## ki-pdt-iodine Illumination converted iodide into reactive iodine. Illuminated Rose bengal plus KI generated free iodine detected with starch. Model: Rose bengal plus 540-nm light; up to 100 mM KI; microbial assays and a mouse skin-abrasion model. Limitations: Local photochemical system, not an effect of oral KI alone. Peroxyiodide intermediates were proposed, not directly established. Evidence location: Full-text mechanistic results, Figure 4A Potassium Iodide Potentiates Antimicrobial Photodynamic Inactivation Mediated by Rose Bengal in In Vitro and In Vivo Studies. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28438946/ · DOI 10.1128/aac.00467-17
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.