Component

Red yeast rice

Context-specific entity; species, compartment and exposure are stated on each claim.

4 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Twelve products labeled 600 mg per capsule contained 0.00–2.30 mg monacolin KA per capsule, alongside variable lactone and total monacolins.

    Red yeast rice → Lovastatin hydroxy acid / monacolin KA source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Commercial formulations analyzed in 2006–2008.
    limitations
    Do not infer acid/lactone proportions from the red yeast rice mass on a label.
    nutrient_topic
    Red yeast rice collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Red yeast rice
    plain_language
    Acid-form content also varied.
    primary_references
    [20975018] Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! · 2010 · https://pubmed.ncbi.nlm.nih.gov/20975018/ · DOI 10.1001/archinternmed.2010.382

    Red yeast rice: constituents, mevalonate, CoQ and product-specific interactions (2026-09-20) · lines 28–34

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Commercial formulations analyzed in 2006–2008. · source_derived_draft · unverified_draft

    ## red-yeast-rice-acid-variability Acid-form content also varied. Twelve products labeled 600 mg per capsule contained 0.00–2.30 mg monacolin KA per capsule, alongside variable lactone and total monacolins. Model: Commercial formulations analyzed in 2006–2008. Limitations: Do not infer acid/lactone proportions from the red yeast rice mass on a label. Evidence access: Primary abstract [20975018] Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! · 2010 · https://pubmed.ncbi.nlm.nih.gov/20975018/ · DOI 10.1001/archinternmed.2010.382
    Complete structured claim and evidence

  2. Four of twelve analyzed red yeast rice formulations had elevated citrinin levels in the reported survey.

    Red yeast rice → Citrinin source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    HPLC-MS/MS product survey.
    limitations
    This does not establish contamination of every product or a human toxicity threshold.
    nutrient_topic
    Red yeast rice collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Red yeast rice
    plain_language
    The contaminant was present in some tested products.
    primary_references
    [20975018] Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! · 2010 · https://pubmed.ncbi.nlm.nih.gov/20975018/ · DOI 10.1001/archinternmed.2010.382

    Red yeast rice: constituents, mevalonate, CoQ and product-specific interactions (2026-09-20) · lines 36–42

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · HPLC-MS/MS product survey. · source_derived_draft · unverified_draft

    ## red-yeast-rice-citrinin-detection The contaminant was present in some tested products. Four of twelve analyzed red yeast rice formulations had elevated citrinin levels in the reported survey. Model: HPLC-MS/MS product survey. Limitations: This does not establish contamination of every product or a human toxicity threshold. Evidence access: Primary abstract [20975018] Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! · 2010 · https://pubmed.ncbi.nlm.nih.gov/20975018/ · DOI 10.1001/archinternmed.2010.382
    Complete structured claim and evidence

  3. The 28-brand analytical study treated monacolin K in red yeast rice as chemically identical to lovastatin.

    Red yeast rice → Lovastatin / monacolin K lactone source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    2017 commercial-product chemical analysis.
    limitations
    Chemical identity does not make the whole mixture identical to a lovastatin tablet or establish equal exposure.
    nutrient_topic
    Red yeast rice collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Red yeast rice
    plain_language
    A constituent can be the same molecule as a prescription drug.
    primary_references
    [28641460] Variability in strength of red yeast rice supplements purchased from mainstream retailers. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28641460/ · DOI 10.1177/2047487317715714

    Red yeast rice: constituents, mevalonate, CoQ and product-specific interactions (2026-09-20) · lines 12–18

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · 2017 commercial-product chemical analysis. · source_derived_draft · unverified_draft

    ## red-yeast-rice-monacolin-identity A constituent can be the same molecule as a prescription drug. The 28-brand analytical study treated monacolin K in red yeast rice as chemically identical to lovastatin. Model: 2017 commercial-product chemical analysis. Limitations: Chemical identity does not make the whole mixture identical to a lovastatin tablet or establish equal exposure. Evidence access: Primary abstract [28641460] Variability in strength of red yeast rice supplements purchased from mainstream retailers. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28641460/ · DOI 10.1177/2047487317715714
    Complete structured claim and evidence

  4. Monacolin K was undetected in two of 28 brands; the other 26 ranged from 0.09 to 5.48 mg per 1,200 mg red yeast rice.

    Red yeast rice → Lovastatin / monacolin K lactone source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    UHPLC-based analysis of products purchased for the 2017 study.
    limitations
    A historical sample, not a measurement of current products or batches.
    nutrient_topic
    Red yeast rice collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Red yeast rice
    plain_language
    Equal masses of product delivered very different measured amounts.
    primary_references
    [28641460] Variability in strength of red yeast rice supplements purchased from mainstream retailers. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28641460/ · DOI 10.1177/2047487317715714

    Red yeast rice: constituents, mevalonate, CoQ and product-specific interactions (2026-09-20) · lines 20–26

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · UHPLC-based analysis of products purchased for the 2017 study. · source_derived_draft · unverified_draft

    ## red-yeast-rice-monacolin-variability Equal masses of product delivered very different measured amounts. Monacolin K was undetected in two of 28 brands; the other 26 ranged from 0.09 to 5.48 mg per 1,200 mg red yeast rice. Model: UHPLC-based analysis of products purchased for the 2017 study. Limitations: A historical sample, not a measurement of current products or batches. Evidence access: Primary abstract [28641460] Variability in strength of red yeast rice supplements purchased from mainstream retailers. · 2017 · https://pubmed.ncbi.nlm.nih.gov/28641460/ · DOI 10.1177/2047487317715714
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards