Component

cis-Nasunin

cis-Nasunin. Species, exposure and limitations are retained in each linked claim.

4 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Oral cis-nasunin appeared in plasma in its original acylated form, peaking at 15 minutes.

    cis-Nasunin → Intact nasunin exposure in rat plasma source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"}
    experimental_model
    Oral isomer pharmacokinetics with chromatographic metabolite analysis
    exposure
    Oral purified cis/trans nasunin; plasma follow-up to 8 h
    limitations
    Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    The rat absorbed some intact pigment.
    primary_references
    [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    tissue_or_cell_type
    Plasma and urine

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 718–729

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Oral isomer pharmacokinetics with chromatographic metabolite analysis · source_derived_draft · unverified_draft

    ### nasunin-cis-uptake Oral cis-nasunin appeared in plasma in its original acylated form, peaking at 15 minutes. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The rat absorbed some intact pigment. organism: Rats tissue_or_cell_type: Plasma and urine experimental_model: Oral isomer pharmacokinetics with chromatographic metabolite analysis limitations: Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion. exposure: Oral purified cis/trans nasunin; plasma follow-up to 8 h evidence_span: {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"} [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    Complete structured claim and evidence

  2. Dose-normalized peak concentrations and areas under the curve did not significantly differ between isomers.

    cis-Nasunin → trans-Nasunin source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"}
    experimental_model
    Oral isomer pharmacokinetics with chromatographic metabolite analysis
    exposure
    Oral purified cis/trans nasunin; plasma follow-up to 8 h
    limitations
    Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    Neither isomer showed a clear advantage in this comparison.
    primary_references
    [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    tissue_or_cell_type
    Plasma and urine

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 744–755

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Oral isomer pharmacokinetics with chromatographic metabolite analysis · source_derived_draft · unverified_draft

    ### nasunin-isomer-comparison Dose-normalized peak concentrations and areas under the curve did not significantly differ between isomers. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Neither isomer showed a clear advantage in this comparison. organism: Rats tissue_or_cell_type: Plasma and urine experimental_model: Oral isomer pharmacokinetics with chromatographic metabolite analysis limitations: Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion. exposure: Oral purified cis/trans nasunin; plasma follow-up to 8 h evidence_span: {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"} [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    Complete structured claim and evidence

  3. The isolated cis and trans forms interconverted under room light.

    cis-Nasunin → trans-Nasunin source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/16302764.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e", "start_char": 0, "end_char": 759, "text_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e"}
    experimental_model
    Purification, mass spectrometry and NMR
    exposure
    Acidified methanolic extract; room-light exposure
    limitations
    Cis/trans refers to the p-coumaroyl moiety. Interconversion during handling can change the tested preparation; this is not human metabolism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Solanum melongena
    plain_language
    Sample illumination can alter the isomer mixture.
    primary_references
    [nasunin-p16302764] Nasunin from eggplant consists of cis-trans isomers of delphinidin 3-[4-(p-coumaroyl)-L-rhamnosyl (1-->6)glucopyranoside]-5-glucopyranoside. (2005). https://pubmed.ncbi.nlm.nih.gov/16302764/ DOI: 10.1021/jf051841y
    tissue_or_cell_type
    Eggplant peel pigments

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 120–131

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purification, mass spectrometry and NMR · source_derived_draft · unverified_draft

    ### nasunin-photoisomerization The isolated cis and trans forms interconverted under room light. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Sample illumination can alter the isomer mixture. organism: Solanum melongena tissue_or_cell_type: Eggplant peel pigments experimental_model: Purification, mass spectrometry and NMR limitations: Cis/trans refers to the p-coumaroyl moiety. Interconversion during handling can change the tested preparation; this is not human metabolism. exposure: Acidified methanolic extract; room-light exposure evidence_span: {"source_cache": "artifacts/nasunin-research/16302764.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e", "start_char": 0, "end_char": 759, "text_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e"} [nasunin-p16302764] Nasunin from eggplant consists of cis-trans isomers of delphinidin 3-[4-(p-coumaroyl)-L-rhamnosyl (1-->6)glucopyranoside]-5-glucopyranoside. (2005). https://pubmed.ncbi.nlm.nih.gov/16302764/ DOI: 10.1021/jf051841y
    Complete structured claim and evidence

What acts on it

  1. Nasunin isolated from eggplant included a cis-p-coumaroyl isomer.

    Nasunin → cis-Nasunin source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/16302764.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e", "start_char": 0, "end_char": 759, "text_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e"}
    experimental_model
    Purification, mass spectrometry and NMR
    exposure
    Acidified methanolic extract; room-light exposure
    limitations
    Cis/trans refers to the p-coumaroyl moiety. Interconversion during handling can change the tested preparation; this is not human metabolism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Solanum melongena
    plain_language
    One name can cover two distinguishable molecular forms.
    primary_references
    [nasunin-p16302764] Nasunin from eggplant consists of cis-trans isomers of delphinidin 3-[4-(p-coumaroyl)-L-rhamnosyl (1-->6)glucopyranoside]-5-glucopyranoside. (2005). https://pubmed.ncbi.nlm.nih.gov/16302764/ DOI: 10.1021/jf051841y
    tissue_or_cell_type
    Eggplant peel pigments

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 94–105

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purification, mass spectrometry and NMR · source_derived_draft · unverified_draft

    ### nasunin-cis-identity Nasunin isolated from eggplant included a cis-p-coumaroyl isomer. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: One name can cover two distinguishable molecular forms. organism: Solanum melongena tissue_or_cell_type: Eggplant peel pigments experimental_model: Purification, mass spectrometry and NMR limitations: Cis/trans refers to the p-coumaroyl moiety. Interconversion during handling can change the tested preparation; this is not human metabolism. exposure: Acidified methanolic extract; room-light exposure evidence_span: {"source_cache": "artifacts/nasunin-research/16302764.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e", "start_char": 0, "end_char": 759, "text_sha256": "4a79be9e5b34aba2c189fcde3f22fe9142f8b87408f33caeefc9283841ec894e"} [nasunin-p16302764] Nasunin from eggplant consists of cis-trans isomers of delphinidin 3-[4-(p-coumaroyl)-L-rhamnosyl (1-->6)glucopyranoside]-5-glucopyranoside. (2005). https://pubmed.ncbi.nlm.nih.gov/16302764/ DOI: 10.1021/jf051841y
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

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