Component
Study-specific tomato paste food intervention
Study-specific tomato paste food intervention. Species, exposure and limitations are retained in each linked claim.
5 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Tomato paste produced a 3.8-fold higher chylomicron lycopene AUC than fresh tomatoes with matched lycopene and corn oil.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/9209178.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9e44d803f52bf022b12d9bbffbe5e2832be523d37ccfbcf2187296c5fb89200f", "start_char": 0, "end_char": 985, "text_sha256": "9e44d803f52bf022b12d9bbffbe5e2832be523d37ccfbcf2187296c5fb89200f"}
- experimental_model
- Human single-meal bioavailability comparison
- exposure
- 23 mg lycopene from fresh tomato or paste with 15 g corn oil
- limitations
- Both meals contained oil; does not isolate an oil effect or establish all heating improves availability.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human
- plain_language
- Food structure matters even when the amount of lycopene is the same.
- primary_references
- [lycopene-p9209178] Lycopene is more bioavailable from tomato paste than from fresh tomatoes. (1997). https://pubmed.ncbi.nlm.nih.gov/9209178/ DOI: 10.1093/ajcn/66.1.116
- tissue_or_cell_type
- Chylomicron fraction
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 169–180
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Human single-meal bioavailability comparison · source_derived_draft · unverified_draft
### lycopene-paste-absorption Tomato paste produced a 3.8-fold higher chylomicron lycopene AUC than fresh tomatoes with matched lycopene and corn oil. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: Food structure matters even when the amount of lycopene is the same. organism: Human tissue_or_cell_type: Chylomicron fraction experimental_model: Human single-meal bioavailability comparison limitations: Both meals contained oil; does not isolate an oil effect or establish all heating improves availability. exposure: 23 mg lycopene from fresh tomato or paste with 15 g corn oil evidence_span: {"source_cache": "artifacts/lycopene-research/9209178.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9e44d803f52bf022b12d9bbffbe5e2832be523d37ccfbcf2187296c5fb89200f", "start_char": 0, "end_char": 985, "text_sha256": "9e44d803f52bf022b12d9bbffbe5e2832be523d37ccfbcf2187296c5fb89200f"} [lycopene-p9209178] Lycopene is more bioavailable from tomato paste than from fresh tomatoes. (1997). https://pubmed.ncbi.nlm.nih.gov/9209178/ DOI: 10.1093/ajcn/66.1.116
Complete structured claim and evidenceTomato paste increased instrumental erythema D30 versus control, P=0.03.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"}
- experimental_model
- Randomized tomato-paste versus olive-oil trial
- exposure
- 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks
- limitations
- Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 20 women with skin phototypes I/II
- plain_language
- A measured redness response was less sensitive after the food intervention.
- primary_references
- [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
- tissue_or_cell_type
- UV-exposed skin and biopsies
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1183–1194
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized tomato-paste versus olive-oil trial · source_derived_draft · unverified_draft
### lycopene-skin-d30 Tomato paste increased instrumental erythema D30 versus control, P=0.03. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A measured redness response was less sensitive after the food intervention. organism: Human, 20 women with skin phototypes I/II tissue_or_cell_type: UV-exposed skin and biopsies experimental_model: Randomized tomato-paste versus olive-oil trial limitations: Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer. exposure: 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks evidence_span: {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"} [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
Complete structured claim and evidenceThe visually assessed minimal erythema dose did not differ significantly between groups.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"}
- experimental_model
- Randomized tomato-paste versus olive-oil trial
- exposure
- 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks
- limitations
- Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 20 women with skin phototypes I/II
- plain_language
- A different redness endpoint did not show the same statistical result.
- primary_references
- [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
- tissue_or_cell_type
- UV-exposed skin and biopsies
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1196–1207
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized tomato-paste versus olive-oil trial · source_derived_draft · unverified_draft
### lycopene-skin-med-null The visually assessed minimal erythema dose did not differ significantly between groups. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A different redness endpoint did not show the same statistical result. organism: Human, 20 women with skin phototypes I/II tissue_or_cell_type: UV-exposed skin and biopsies experimental_model: Randomized tomato-paste versus olive-oil trial limitations: Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer. exposure: 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks evidence_span: {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"} [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
Complete structured claim and evidenceTomato paste reduced UV-induced MMP-1 expression versus control, P=0.04.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"}
- experimental_model
- Randomized tomato-paste versus olive-oil trial
- exposure
- 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks
- limitations
- Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 20 women with skin phototypes I/II
- plain_language
- A marker linked to matrix breakdown was lower.
- primary_references
- [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
- tissue_or_cell_type
- UV-exposed skin and biopsies
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1209–1220
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized tomato-paste versus olive-oil trial · source_derived_draft · unverified_draft
### lycopene-skin-mmp1 Tomato paste reduced UV-induced MMP-1 expression versus control, P=0.04. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A marker linked to matrix breakdown was lower. organism: Human, 20 women with skin phototypes I/II tissue_or_cell_type: UV-exposed skin and biopsies experimental_model: Randomized tomato-paste versus olive-oil trial limitations: Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer. exposure: 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks evidence_span: {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"} [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
Complete structured claim and evidenceThe UV-associated mitochondrial DNA 3895-base-pair deletion decreased after tomato-paste supplementation.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"}
- experimental_model
- Randomized tomato-paste versus olive-oil trial
- exposure
- 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks
- limitations
- Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 20 women with skin phototypes I/II
- plain_language
- A measured mitochondrial DNA damage endpoint improved.
- primary_references
- [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
- tissue_or_cell_type
- UV-exposed skin and biopsies
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1222–1233
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized tomato-paste versus olive-oil trial · source_derived_draft · unverified_draft
### lycopene-skin-mtdna The UV-associated mitochondrial DNA 3895-base-pair deletion decreased after tomato-paste supplementation. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A measured mitochondrial DNA damage endpoint improved. organism: Human, 20 women with skin phototypes I/II tissue_or_cell_type: UV-exposed skin and biopsies experimental_model: Randomized tomato-paste versus olive-oil trial limitations: Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer. exposure: 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks evidence_span: {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"} [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.