Component
UV-induced skin MMP-1 expression
UV-induced skin MMP-1 expression. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Tomato paste reduced UV-induced MMP-1 expression versus control, P=0.04.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"}
- experimental_model
- Randomized tomato-paste versus olive-oil trial
- exposure
- 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks
- limitations
- Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer.
- nutrient_topic
- Lycopene research collection; topical membership is not evidence of a direct dietary effect. · Lycopene
- organism
- Human, 20 women with skin phototypes I/II
- plain_language
- A marker linked to matrix breakdown was lower.
- primary_references
- [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
- tissue_or_cell_type
- UV-exposed skin and biopsies
Lycopene: absorption, metabolism, nutrient connections and human outcomes (2026-09-17) · lines 1209–1220
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized tomato-paste versus olive-oil trial · source_derived_draft · unverified_draft
### lycopene-skin-mmp1 Tomato paste reduced UV-induced MMP-1 expression versus control, P=0.04. Condition category: normal nutrient_topic: Lycopene research collection; topical membership is not evidence of a direct dietary effect. plain_language: A marker linked to matrix breakdown was lower. organism: Human, 20 women with skin phototypes I/II tissue_or_cell_type: UV-exposed skin and biopsies experimental_model: Randomized tomato-paste versus olive-oil trial limitations: Whole food exposure; UV endpoints differ; not evidence that lycopene replaces sunscreen or prevents skin cancer. exposure: 55 g tomato paste providing 16 mg lycopene daily in olive oil for 12 weeks evidence_span: {"source_cache": "artifacts/lycopene-research/20854436.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba", "start_char": 0, "end_char": 2063, "text_sha256": "70a295ef309afb9296521357fe29b70f532c2fd215687c918b94ee027aa707ba"} [lycopene-p20854436] Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. (2011). https://pubmed.ncbi.nlm.nih.gov/20854436/ DOI: 10.1111/j.1365-2133.2010.10057.x
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.