Human post-meal plasma lutein response: molecular mechanisms & dependencies

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

Human evidence only

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

The high-egg salad meal increased lutein/zeaxanthin lipoprotein AUC about four- to fivefold versus salad without egg.
Salad plus 150 g scrambled whole eggs in the 2015 crossover study → Human post-meal plasma lutein response source_derived_draftungraded
Experimental context and source evidence
evidence_span
{"source_cache": "artifacts/lutein-research/26016861.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "c275d8263df6d127f722fc47b45e9bc513c6d871653afbc878bc50a911b1df55", "start_char": 0, "end_char": 2045, "text_sha256": "c275d8263df6d127f722fc47b45e9bc513c6d871653afbc878bc50a911b1df55"}
experimental_model
Randomized three-meal crossover trial
exposure
Salad plus 0, 75 or 150 g scrambled whole eggs; ten-hour sampling
limitations
Eggs supplied both fat and carotenoids; the experiment does not isolate a choline effect. Published erratum 10.3945/ajcn.115.120956 corrects an author affiliation to Department of Nutrition Science; it does not change the trial outcomes. Correction: https://doi.org/10.3945/ajcn.115.120956 .
nutrient_topic
Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
organism
16 healthy young men
plain_language
The whole-food meal increased carotenoid appearance in blood.
primary_references
[lutein-p26016861] Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables. (2015). https://pubmed.ncbi.nlm.nih.gov/26016861/ DOI: 10.3945/ajcn.115.111062
tissue_or_cell_type
Post-meal triglyceride-rich lipoproteins
Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 593–604
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized three-meal crossover trial · source_derived_draft · unverified_draft
### lutein-egg-matrix The high-egg salad meal increased lutein/zeaxanthin lipoprotein AUC about four- to fivefold versus salad without egg. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: The whole-food meal increased carotenoid appearance in blood. organism: 16 healthy young men tissue_or_cell_type: Post-meal triglyceride-rich lipoproteins experimental_model: Randomized three-meal crossover trial limitations: Eggs supplied both fat and carotenoids; the experiment does not isolate a choline effect. Published erratum 10.3945/ajcn.115.120956 corrects an author affiliation to Department of Nutrition Science; it does not change the trial outcomes. Correction: https://doi.org/10.3945/ajcn.115.120956 . exposure: Salad plus 0, 75 or 150 g scrambled whole eggs; ten-hour sampling evidence_span: {"source_cache": "artifacts/lutein-research/26016861.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "c275d8263df6d127f722fc47b45e9bc513c6d871653afbc878bc50a911b1df55", "start_char": 0, "end_char": 2045, "text_sha256": "c275d8263df6d127f722fc47b45e9bc513c6d871653afbc878bc50a911b1df55"} [lutein-p26016861] Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables. (2015). https://pubmed.ncbi.nlm.nih.gov/26016861/ DOI: 10.3945/ajcn.115.111062
Complete structured claim and evidence
Lutein AUC was reduced with the tested fibers, including pectin.
Pectin, structurally heterogeneous plant polysaccharides → Human post-meal plasma lutein response source_derived_draftungraded
Experimental context and source evidence
evidence_span
{"source_cache": "artifacts/pectin-research/10573545.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332", "start_char": 0, "end_char": 1340, "text_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332"}
experimental_model
Crossover mixed-carotenoid meal study in six healthy women
exposure
Pectin or other fibers at 0.15 g/kg with a carotenoid and alpha-tocopherol mixture
limitations
Reported effect-size ranges cover multiple fibers, not one pectin-specific estimate. Plasma exposure does not establish long-term deficiency.
nutrient_topic
Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
organism
Homo sapiens
plain_language
The finding also involved lutein.
primary_references
[pectin-p10573545] Some dietary fibers reduce the absorption of carotenoids in women. (1999). https://pubmed.ncbi.nlm.nih.gov/10573545/ DOI: 10.1093/jn/129.12.2170
tissue_or_cell_type
Plasma 24-hour area under the curve
Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 698–709
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Crossover mixed-carotenoid meal study in six healthy women · source_derived_draft · unverified_draft
### pectin-lutein-auc Lutein AUC was reduced with the tested fibers, including pectin. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The finding also involved lutein. organism: Homo sapiens tissue_or_cell_type: Plasma 24-hour area under the curve experimental_model: Crossover mixed-carotenoid meal study in six healthy women limitations: Reported effect-size ranges cover multiple fibers, not one pectin-specific estimate. Plasma exposure does not establish long-term deficiency. exposure: Pectin or other fibers at 0.15 g/kg with a carotenoid and alpha-tocopherol mixture evidence_span: {"source_cache": "artifacts/pectin-research/10573545.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332", "start_char": 0, "end_char": 1340, "text_sha256": "f0828162b0e41d10d79784cea5cc96e55409b4ee80be3afc399132a7ad087332"} [pectin-p10573545] Some dietary fibers reduce the absorption of carotenoids in women. (1999). https://pubmed.ncbi.nlm.nih.gov/10573545/ DOI: 10.1093/jn/129.12.2170
Complete structured claim and evidence

The events it takes part in

A mechanism often involves more than two components. These are the full events, with every participant and its role.

Situations it appears in

Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

Open hypotheses

Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.

This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

Human post-meal plasma lutein response