Component

Iodinated contrast media, study mixture

Study-specific endpoint; inspect claim context for model and measurement.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Salivary hypoiodous acid increased after contrast exposure and its change correlated with iodine load.

    Iodinated contrast media, study mixture → Salivary hypoiodous acid concentration source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The saliva contained more of an oxidized iodine species.
    primary_references
    Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 168–174

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. · source_derived_draft · unverified_draft

    ## ki-saliva-hoi The saliva contained more of an oxidized iodine species. Salivary hypoiodous acid increased after contrast exposure and its change correlated with iodine load. Model: Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. Limitations: Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose. Evidence location: Primary abstract Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8
    Complete structured claim and evidence

  2. After contrast administration, salivary iodide increased relative to baseline.

    Iodinated contrast media, study mixture → Salivary iodide concentration source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    A systemic iodine exposure changed salivary iodide.
    primary_references
    Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 160–166

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. · source_derived_draft · unverified_draft

    ## ki-saliva-iodide A systemic iodine exposure changed salivary iodide. After contrast administration, salivary iodide increased relative to baseline. Model: Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. Limitations: Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose. Evidence location: Primary abstract Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8
    Complete structured claim and evidence

  3. Salivary thiocyanate and hypothiocyanite did not significantly change after contrast exposure.

    Iodinated contrast media, study mixture → Hypothiocyanite / OSCN− source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    Not every component of the defence system increased.
    primary_references
    Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 176–182

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. · source_derived_draft · unverified_draft

    ## ki-saliva-null Not every component of the defence system increased. Salivary thiocyanate and hypothiocyanite did not significantly change after contrast exposure. Model: Paired saliva measurements in 40 coronary-angiography patients exposed to iodinated contrast. Limitations: Contrast exposure is not oral KI; observational chemistry endpoints do not establish infection prevention or a safe effective supplement dose. Evidence location: Primary abstract Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans. · 2022 · https://pubmed.ncbi.nlm.nih.gov/36463312/ · DOI 10.1038/s41598-022-23803-8
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards