Component

Human intestinal strontium absorption

Context-specific entity; species, compartment and exposure are stated on each claim.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. In four renal-failure patients retested after calcitriol 1 microgram/day for ten days, six-hour strontium absorption increased 4.29-fold and calcium absorption 2.4-fold.

    Calcitriol → Human intestinal strontium absorption source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Small before/after subgroup within the dual-tracer study.
    limitations
    Four patients, active hormone and renal impairment; not a universal effect of vitamin D3 supplementation.
    nutrient_topic
    Strontium collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Strontium
    plain_language
    Active vitamin D changed the two absorption responses by different amounts.
    primary_references
    Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the double-radiotracer calcium absorption test. · 1994 · https://pubmed.ncbi.nlm.nih.gov/7955914/ · DOI 10.1042/cs0870363

    Strontium: calcium interactions, cellular mechanisms and mineralization (2026-09-19) · lines 54–60

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Small before/after subgroup within the dual-tracer study. · source_derived_draft · unverified_draft

    ## strontium-calcitriol-absorption Active vitamin D changed the two absorption responses by different amounts. In four renal-failure patients retested after calcitriol 1 microgram/day for ten days, six-hour strontium absorption increased 4.29-fold and calcium absorption 2.4-fold. Model: Small before/after subgroup within the dual-tracer study. Limitations: Four patients, active hormone and renal impairment; not a universal effect of vitamin D3 supplementation. Evidence access: Primary abstract Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the double-radiotracer calcium absorption test. · 1994 · https://pubmed.ncbi.nlm.nih.gov/7955914/ · DOI 10.1042/cs0870363
    Complete structured claim and evidence

  2. Correcting vitamin D deficiency with vitamin D3 did not increase the measured strontium-ranelate absorption in the study of postmenopausal women with low bone mass.

    Cholecalciferol → Human intestinal strontium absorption source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    25 women below 50 nmol/L 25(OH)D and 25 above 75 nmol/L; deficient group retested after repletion.
    limitations
    Mild deficiency, oral overload test and D3 intervention differ from the four-patient calcitriol experiment; not a scientific contradiction or evidence against treating vitamin D deficiency.
    nutrient_topic
    Strontium collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Strontium
    plain_language
    Improving vitamin D status did not automatically improve strontium absorption.
    primary_references
    Vitamin D supplementation and strontium ranelate absorption in postmenopausal women with low bone mass. · 2014 · https://pubmed.ncbi.nlm.nih.gov/24394724/ · DOI 10.1530/EJE-13-0899

    Strontium: calcium interactions, cellular mechanisms and mineralization (2026-09-19) · lines 62–68

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · 25 women below 50 nmol/L 25(OH)D and 25 above 75 nmol/L; deficient group retested after repletion. · source_derived_draft · unverified_draft

    ## strontium-vitamin-d3-null Improving vitamin D status did not automatically improve strontium absorption. Correcting vitamin D deficiency with vitamin D3 did not increase the measured strontium-ranelate absorption in the study of postmenopausal women with low bone mass. Model: 25 women below 50 nmol/L 25(OH)D and 25 above 75 nmol/L; deficient group retested after repletion. Limitations: Mild deficiency, oral overload test and D3 intervention differ from the four-patient calcitriol experiment; not a scientific contradiction or evidence against treating vitamin D deficiency. Evidence access: Primary abstract Vitamin D supplementation and strontium ranelate absorption in postmenopausal women with low bone mass. · 2014 · https://pubmed.ncbi.nlm.nih.gov/24394724/ · DOI 10.1530/EJE-13-0899
    Complete structured claim and evidence

Where it participates (unsigned role)

  1. In 17 patients with osteoporosis or chronic renal failure, mean six-hour fractional absorption was 20.2% for stable strontium versus 37.8% for calcium, despite correlated time courses.

    Strontium ion / Sr2+ → Calcium ion source_derived_draftungraded
    Experimental context and source evidence
    evidence_access
    Primary abstract
    experimental_model
    Consecutive-day dual-tracer tests with standardized meals; ten osteoporosis and seven renal-failure patients.
    limitations
    Small selected sample; nonlinear relationship and meal/carrier doses matter. Accessed abstract is explicitly truncated.
    nutrient_topic
    Strontium collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Strontium
    plain_language
    Strontium can be a calcium tracer surrogate without behaving identically.
    primary_references
    Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the double-radiotracer calcium absorption test. · 1994 · https://pubmed.ncbi.nlm.nih.gov/7955914/ · DOI 10.1042/cs0870363

    Strontium: calcium interactions, cellular mechanisms and mineralization (2026-09-19) · lines 46–52

    AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Consecutive-day dual-tracer tests with standardized meals; ten osteoporosis and seven renal-failure patients. · source_derived_draft · unverified_draft

    ## strontium-absorption-not-identical Strontium can be a calcium tracer surrogate without behaving identically. In 17 patients with osteoporosis or chronic renal failure, mean six-hour fractional absorption was 20.2% for stable strontium versus 37.8% for calcium, despite correlated time courses. Model: Consecutive-day dual-tracer tests with standardized meals; ten osteoporosis and seven renal-failure patients. Limitations: Small selected sample; nonlinear relationship and meal/carrier doses matter. Accessed abstract is explicitly truncated. Evidence access: Primary abstract Stable strontium absorption as a measure of intestinal calcium absorption: comparison with the double-radiotracer calcium absorption test. · 1994 · https://pubmed.ncbi.nlm.nih.gov/7955914/ · DOI 10.1042/cs0870363
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards