Component

Human gamma-nonalactone aroma detection

Species, assay, exposure and limitations are retained on linked claims.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. The reported sensory detection threshold for R-gamma-nonalactone was 66 micrograms/L.

    (R)-Gamma-nonalactone → Human gamma-nonalactone aroma detection source_derived_draftungraded
    Experimental context and source evidence
    dose
    R and S gamma-nonalactone concentration series
    duration
    Threshold-testing interval not specified in abstract
    evidence_access
    Primary PubMed abstract; unresolved method details explicitly retained.
    evidence_scope
    literature_reviewed; model-specific source-derived curation
    experimental_model
    Human sensory detection tests reported with grape/wine enantiomer study
    limitations
    Enantiomer thresholds depend on matrix and protocol. No olfactory receptor identity or general threshold across foods is established.
    nutrient_topic
    Gamma-nonalactone flavor-compound chapter; nutrient and drug interactions retain their experimental settings. · Gamma-nonalactone
    organism
    Human sensory detection tests reported with grape/wine enantiomer study
    plain_language
    The reported sensory detection threshold for R-gamma-nonalactone was 66 micrograms/L.
    primary_references
    Aromatic Potential of Bordeaux Grape Cultivars: Identification and Assays on 4-Oxononanoic Acid, a γ-Nonalactone Precursor. (2020). https://pubmed.ncbi.nlm.nih.gov/32955257/ DOI: 10.1021/acs.jafc.0c04171
    route
    Sensory exposure; exact test matrix and panel size unresolved in accessed abstract
    tissue
    Olfactory perception

    Gamma-nonalactone: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 180–189

    Original AI-assisted curation of eight primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Human sensory detection tests reported with grape/wine enantiomer study · source_derived_draft · unverified_draft

    ## gamma-nonalactone-r-odor-threshold The reported sensory detection threshold for R-gamma-nonalactone was 66 micrograms/L. Model/species: Human sensory detection tests reported with grape/wine enantiomer study Tissue: Olfactory perception Exposure: R and S gamma-nonalactone concentration series Route: Sensory exposure; exact test matrix and panel size unresolved in accessed abstract Duration: Threshold-testing interval not specified in abstract Limits: Enantiomer thresholds depend on matrix and protocol. No olfactory receptor identity or general threshold across foods is established. Primary reference: Aromatic Potential of Bordeaux Grape Cultivars: Identification and Assays on 4-Oxononanoic Acid, a γ-Nonalactone Precursor. (2020). https://pubmed.ncbi.nlm.nih.gov/32955257/ DOI: 10.1021/acs.jafc.0c04171 Access: Primary PubMed abstract; unresolved method details explicitly retained.
    Complete structured claim and evidence

  2. The reported sensory detection threshold for S-gamma-nonalactone was 35 micrograms/L.

    (S)-Gamma-nonalactone → Human gamma-nonalactone aroma detection source_derived_draftungraded
    Experimental context and source evidence
    dose
    R and S gamma-nonalactone concentration series
    duration
    Threshold-testing interval not specified in abstract
    evidence_access
    Primary PubMed abstract; unresolved method details explicitly retained.
    evidence_scope
    literature_reviewed; model-specific source-derived curation
    experimental_model
    Human sensory detection tests reported with grape/wine enantiomer study
    limitations
    Enantiomer thresholds depend on matrix and protocol. No olfactory receptor identity or general threshold across foods is established.
    nutrient_topic
    Gamma-nonalactone flavor-compound chapter; nutrient and drug interactions retain their experimental settings. · Gamma-nonalactone
    organism
    Human sensory detection tests reported with grape/wine enantiomer study
    plain_language
    The reported sensory detection threshold for S-gamma-nonalactone was 35 micrograms/L.
    primary_references
    Aromatic Potential of Bordeaux Grape Cultivars: Identification and Assays on 4-Oxononanoic Acid, a γ-Nonalactone Precursor. (2020). https://pubmed.ncbi.nlm.nih.gov/32955257/ DOI: 10.1021/acs.jafc.0c04171
    route
    Sensory exposure; exact test matrix and panel size unresolved in accessed abstract
    tissue
    Olfactory perception

    Gamma-nonalactone: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 191–200

    Original AI-assisted curation of eight primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Human sensory detection tests reported with grape/wine enantiomer study · source_derived_draft · unverified_draft

    ## gamma-nonalactone-s-odor-threshold The reported sensory detection threshold for S-gamma-nonalactone was 35 micrograms/L. Model/species: Human sensory detection tests reported with grape/wine enantiomer study Tissue: Olfactory perception Exposure: R and S gamma-nonalactone concentration series Route: Sensory exposure; exact test matrix and panel size unresolved in accessed abstract Duration: Threshold-testing interval not specified in abstract Limits: Enantiomer thresholds depend on matrix and protocol. No olfactory receptor identity or general threshold across foods is established. Primary reference: Aromatic Potential of Bordeaux Grape Cultivars: Identification and Assays on 4-Oxononanoic Acid, a γ-Nonalactone Precursor. (2020). https://pubmed.ncbi.nlm.nih.gov/32955257/ DOI: 10.1021/acs.jafc.0c04171 Access: Primary PubMed abstract; unresolved method details explicitly retained.
    Complete structured claim and evidence

  3. The gamma-nonalactone aroma detection threshold in 5% sucrose was reported as 0.0047 mg/kg solution.

    Gamma-nonalactone → Human gamma-nonalactone aroma detection source_derived_draftungraded
    Experimental context and source evidence
    dose
    Gamma-nonalactone serial dilution; reported threshold 0.0047 mg/kg
    duration
    Repeated threshold trials
    evidence_access
    Primary full-text methods/results inspected; PubMed metadata where indexed.
    evidence_scope
    literature_reviewed; model-specific source-derived curation
    experimental_model
    Ten trained human sensory evaluators
    limitations
    The water comparison was a literature reference, not a matched experiment. Do not equate detection threshold with the much larger sweetness-optimization concentration.
    nutrient_topic
    Gamma-nonalactone flavor-compound chapter; nutrient and drug interactions retain their experimental settings. · Gamma-nonalactone
    organism
    Ten trained human sensory evaluators
    plain_language
    The gamma-nonalactone aroma detection threshold in 5% sucrose was reported as 0.0047 mg/kg solution.
    primary_references
    Sweetness enhancement and mechanism by sweet aroma compounds in the sucrose solution using sensory, electronic tongue, molecular docking, and molecular dynamics simulation. (2026). https://pubmed.ncbi.nlm.nih.gov/41884462/ DOI: 10.1016/j.fochx.2026.103753
    route
    Sensory testing in sucrose solution
    tissue
    Three-alternative forced-choice aroma detection in 5% sucrose

    Gamma-nonalactone: mechanisms, molecular forms and cross-actor connections (2026-09-20) · lines 246–255

    Original AI-assisted curation of eight primary studies. Study-specific citations, negative findings and limitations retained. Not publisher full text. · supports · Ten trained human sensory evaluators · source_derived_draft · unverified_draft

    ## gamma-nonalactone-sucrose-aroma-threshold The gamma-nonalactone aroma detection threshold in 5% sucrose was reported as 0.0047 mg/kg solution. Model/species: Ten trained human sensory evaluators Tissue: Three-alternative forced-choice aroma detection in 5% sucrose Exposure: Gamma-nonalactone serial dilution; reported threshold 0.0047 mg/kg Route: Sensory testing in sucrose solution Duration: Repeated threshold trials Limits: The water comparison was a literature reference, not a matched experiment. Do not equate detection threshold with the much larger sweetness-optimization concentration. Primary reference: Sweetness enhancement and mechanism by sweet aroma compounds in the sucrose solution using sensory, electronic tongue, molecular docking, and molecular dynamics simulation. (2026). https://pubmed.ncbi.nlm.nih.gov/41884462/ DOI: 10.1016/j.fochx.2026.103753 Access: Primary full-text methods/results inspected; PubMed metadata where indexed.
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards