Component

Delphinidin

Delphinidin. Species, exposure and limitations are retained in each linked claim.

7 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Delphinidin and delphinidin 3-glucoside were not detected in plasma during the eight-hour follow-up.

    Nasunin → Delphinidin source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"}
    experimental_model
    Oral isomer pharmacokinetics with chromatographic metabolite analysis
    exposure
    Oral purified cis/trans nasunin; plasma follow-up to 8 h
    limitations
    Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    Absence in this assay does not prove they can never be formed.
    primary_references
    [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    tissue_or_cell_type
    Plasma and urine

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 783–794

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Oral isomer pharmacokinetics with chromatographic metabolite analysis · source_derived_draft · unverified_draft

    ### nasunin-aglycone-nondetection Delphinidin and delphinidin 3-glucoside were not detected in plasma during the eight-hour follow-up. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Absence in this assay does not prove they can never be formed. organism: Rats tissue_or_cell_type: Plasma and urine experimental_model: Oral isomer pharmacokinetics with chromatographic metabolite analysis limitations: Dose-normalized Cmax/AUC comparison is not absolute oral bioavailability. Nondetection applies to the tested analytes, method and window; no human or blood-brain-barrier conclusion. exposure: Oral purified cis/trans nasunin; plasma follow-up to 8 h evidence_span: {"source_cache": "artifacts/nasunin-research/16848510.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a", "start_char": 0, "end_char": 1308, "text_sha256": "72244518913802f8f2018e3e6e7add9914294e49c58b9e9733c26a550e86479a"} [nasunin-p16848510] Gastrointestinal uptake of nasunin, acylated anthocyanin in eggplant. (2006). https://pubmed.ncbi.nlm.nih.gov/16848510/ DOI: 10.1021/jf060238s
    Complete structured claim and evidence

Where it participates (unsigned role)

  1. Nasunin inhibited carotene bleaching in the linoleic-acid/lipoxygenase assay at pH 7.

    Nasunin → Carotene bleaching in the linoleic-acid/lipoxygenase assay source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/oxidation1993.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee", "start_char": 0, "end_char": 1041, "text_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee"}
    experimental_model
    Carotene bleaching and linoleic acid autoxidation assays
    exposure
    Carotene assay pH 7; linoleic acid autoxidation pH 2.8
    limitations
    The structure-activity interpretation is tentative and assay-specific; no vitamin A absorption or systemic vitamin-sparing effect was tested.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Cell-free chemistry
    plain_language
    A food-model assay connects this pigment to oxidation of another pigment.
    primary_references
    [nasunin-poxidation1993] Antioxidative Activity of Nasunin in Chouja-nasu (Little Eggplant, Solanum melongena L. 'Chouja'). (1993). https://www.jstage.jst.go.jp/article/nskkk1962/40/2/40_2_138/_article DOI: 10.3136/nskkk1962.40.138
    tissue_or_cell_type
    Pigment and lipid oxidation

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 601–612

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Carotene bleaching and linoleic acid autoxidation assays · source_derived_draft · unverified_draft

    ### nasunin-carotene-bleaching Nasunin inhibited carotene bleaching in the linoleic-acid/lipoxygenase assay at pH 7. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A food-model assay connects this pigment to oxidation of another pigment. organism: Cell-free chemistry tissue_or_cell_type: Pigment and lipid oxidation experimental_model: Carotene bleaching and linoleic acid autoxidation assays limitations: The structure-activity interpretation is tentative and assay-specific; no vitamin A absorption or systemic vitamin-sparing effect was tested. exposure: Carotene assay pH 7; linoleic acid autoxidation pH 2.8 evidence_span: {"source_cache": "artifacts/nasunin-research/oxidation1993.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee", "start_char": 0, "end_char": 1041, "text_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee"} [nasunin-poxidation1993] Antioxidative Activity of Nasunin in Chouja-nasu (Little Eggplant, Solanum melongena L. 'Chouja'). (1993). https://www.jstage.jst.go.jp/article/nskkk1962/40/2/40_2_138/_article DOI: 10.3136/nskkk1962.40.138
    Complete structured claim and evidence

  2. Serum total cholesterol tended to decrease with nasunin.

    Nasunin → Rat serum total cholesterol source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"}
    experimental_model
    Cholesterol-enriched feeding comparison
    exposure
    Nasunin versus delphinidin supplementation
    limitations
    The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    The reported direction remains labeled as a trend.
    primary_references
    [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    tissue_or_cell_type
    Serum lipids and fecal excretion

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 939–950

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Cholesterol-enriched feeding comparison · source_derived_draft · unverified_draft

    ### nasunin-cholesterol-trend Serum total cholesterol tended to decrease with nasunin. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The reported direction remains labeled as a trend. organism: Rats tissue_or_cell_type: Serum lipids and fecal excretion experimental_model: Cholesterol-enriched feeding comparison limitations: The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism. exposure: Nasunin versus delphinidin supplementation evidence_span: {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"} [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    Complete structured claim and evidence

  3. Fecal bile-acid excretion tended to increase; nasunin and delphinidin effects did not differ.

    Nasunin → Rat fecal bile-acid excretion source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"}
    experimental_model
    Cholesterol-enriched feeding comparison
    exposure
    Nasunin versus delphinidin supplementation
    limitations
    The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    The comparison does not establish a unique nasunin advantage.
    primary_references
    [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    tissue_or_cell_type
    Serum lipids and fecal excretion

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 978–989

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Cholesterol-enriched feeding comparison · source_derived_draft · unverified_draft

    ### nasunin-fecal-bile-trend Fecal bile-acid excretion tended to increase; nasunin and delphinidin effects did not differ. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The comparison does not establish a unique nasunin advantage. organism: Rats tissue_or_cell_type: Serum lipids and fecal excretion experimental_model: Cholesterol-enriched feeding comparison limitations: The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism. exposure: Nasunin versus delphinidin supplementation evidence_span: {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"} [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    Complete structured claim and evidence

  4. Fecal cholesterol excretion tended to increase.

    Nasunin → Rat fecal cholesterol excretion source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"}
    experimental_model
    Cholesterol-enriched feeding comparison
    exposure
    Nasunin versus delphinidin supplementation
    limitations
    The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    This supports a question about intestinal handling without proving the mechanism.
    primary_references
    [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    tissue_or_cell_type
    Serum lipids and fecal excretion

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 965–976

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Cholesterol-enriched feeding comparison · source_derived_draft · unverified_draft

    ### nasunin-fecal-cholesterol-trend Fecal cholesterol excretion tended to increase. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This supports a question about intestinal handling without proving the mechanism. organism: Rats tissue_or_cell_type: Serum lipids and fecal excretion experimental_model: Cholesterol-enriched feeding comparison limitations: The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism. exposure: Nasunin versus delphinidin supplementation evidence_span: {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"} [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    Complete structured claim and evidence

  5. Serum HDL cholesterol tended to increase.

    Nasunin → Rat serum HDL cholesterol source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"}
    experimental_model
    Cholesterol-enriched feeding comparison
    exposure
    Nasunin versus delphinidin supplementation
    limitations
    The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Rats
    plain_language
    This result is also a trend.
    primary_references
    [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    tissue_or_cell_type
    Serum lipids and fecal excretion

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 952–963

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Cholesterol-enriched feeding comparison · source_derived_draft · unverified_draft

    ### nasunin-hdl-trend Serum HDL cholesterol tended to increase. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This result is also a trend. organism: Rats tissue_or_cell_type: Serum lipids and fecal excretion experimental_model: Cholesterol-enriched feeding comparison limitations: The abstract reports trends, not established significant clinical effects. Proposed reduced absorption was an interpretation, not a demonstrated transporter mechanism. exposure: Nasunin versus delphinidin supplementation evidence_span: {"source_cache": "artifacts/nasunin-research/lipids1994.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4", "start_char": 0, "end_char": 980, "text_sha256": "5f7c22d653590116df8a923aba127ecd7c7baa3d0b2224df4e73b83d11361cc4"} [nasunin-plipids1994] Effects of Dietary Nasunin on the Serum Cholesterol Level in Rats (1994). https://www.jstage.jst.go.jp/article/bbb1992/58/3/58_3_570/_article/-char/en DOI: 10.1271/bbb.58.570
    Complete structured claim and evidence

  6. Nasunin inhibited linoleic acid autoxidation at pH 2.8 more strongly than delphinidin.

    Nasunin → Linoleic acid autoxidation source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/nasunin-research/oxidation1993.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee", "start_char": 0, "end_char": 1041, "text_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee"}
    experimental_model
    Carotene bleaching and linoleic acid autoxidation assays
    exposure
    Carotene assay pH 7; linoleic acid autoxidation pH 2.8
    limitations
    The structure-activity interpretation is tentative and assay-specific; no vitamin A absorption or systemic vitamin-sparing effect was tested.
    nutrient_topic
    Nasunin research collection; topical membership is not evidence of a direct dietary effect. · Nasunin
    organism
    Cell-free chemistry
    plain_language
    Chemical decorations altered performance in this acidic assay.
    primary_references
    [nasunin-poxidation1993] Antioxidative Activity of Nasunin in Chouja-nasu (Little Eggplant, Solanum melongena L. 'Chouja'). (1993). https://www.jstage.jst.go.jp/article/nskkk1962/40/2/40_2_138/_article DOI: 10.3136/nskkk1962.40.138
    tissue_or_cell_type
    Pigment and lipid oxidation

    Nasunin: identity, redox chemistry and nutrient connections (2026-09-17) · lines 614–625

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Carotene bleaching and linoleic acid autoxidation assays · source_derived_draft · unverified_draft

    ### nasunin-linoleate-autoxidation Nasunin inhibited linoleic acid autoxidation at pH 2.8 more strongly than delphinidin. Condition category: normal nutrient_topic: Nasunin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Chemical decorations altered performance in this acidic assay. organism: Cell-free chemistry tissue_or_cell_type: Pigment and lipid oxidation experimental_model: Carotene bleaching and linoleic acid autoxidation assays limitations: The structure-activity interpretation is tentative and assay-specific; no vitamin A absorption or systemic vitamin-sparing effect was tested. exposure: Carotene assay pH 7; linoleic acid autoxidation pH 2.8 evidence_span: {"source_cache": "artifacts/nasunin-research/oxidation1993.publisher-abstract.txt", "locator": "Primary publisher abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee", "start_char": 0, "end_char": 1041, "text_sha256": "f5cd9a7913480b3dabe167e043aa03028e74ba6d0a57ada4ca50773ee9b16dee"} [nasunin-poxidation1993] Antioxidative Activity of Nasunin in Chouja-nasu (Little Eggplant, Solanum melongena L. 'Chouja'). (1993). https://www.jstage.jst.go.jp/article/nskkk1962/40/2/40_2_138/_article DOI: 10.3136/nskkk1962.40.138
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards