Component
Bilberry extract with 25% anthocyanosides in Muth 2000
Bilberry extract with 25% anthocyanosides in Muth 2000. Interpret through the linked experimental species, preparation, compartment and exposure; no universal causal effect is implied.
3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Bilberry extract did not improve night contrast sensitivity in the controlled healthy-young-men crossover trial.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract reviewed; full methods, figures, exact doses or endpoint-specific species assignments may remain unextracted.
- experimental_contrast
- {"intervention": "Bilberry extract for 21 days", "comparator": "Placebo in crossover", "endpoint": "Bilberry extract did not improve night contrast sensitivity in the controlled healthy-young-men crossover trial.", "effect_direction": "no_detected_change", "combination": "single", "conditions": []} Explicit extracted experimental comparison; source-derived draft.
- experimental_model
- 15 men, 160 mg 25%-anthocyanoside bilberry extract three times daily, 21 days, washout/crossover.
- interpretation_status
- Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
- limitations
- Specific preparation and healthy population; not all eye diseases or all anthocyanin structures.
- plain_language
- Bilberry extract did not improve night contrast sensitivity in the controlled healthy-young-men crossover trial.
- primary_references
- The effect of bilberry nutritional supplementation on night visual acuity and contrast sensitivity. | 2000 | PMID 10767671 | https://pubmed.ncbi.nlm.nih.gov/10767671/
- source_locator
- Reviewed reference lines 98-98; exact primary location described in quoted passage where extracted.
Anthocyanins: detailed mechanisms of action (reviewed 4 October 2026) · lines 98–98
Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · 15 men, 160 mg 25%-anthocyanoside bilberry extract three times daily, 21 days, washout/crossover. · source_derived_draft · unverified_draft
**Controlled human night-vision results were negative.** A 15-man crossover trial used 160 mg bilberry extract containing 25% anthocyanosides three times daily for 21 days, with a washout and crossover. Night visual acuity and contrast sensitivity did not improve versus placebo. This constrains that preparation in healthy young men; it is not a finding about all eye diseases. Wartime anecdotes are not substitutes for this comparison. [Muth et al., 2000](https://pubmed.ncbi.nlm.nih.gov/10767671/).
Complete structured claim and evidenceBilberry extract did not improve night visual acuity in the controlled healthy-young-men crossover trial.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract reviewed; full methods, figures, exact doses or endpoint-specific species assignments may remain unextracted.
- experimental_contrast
- {"intervention": "Bilberry extract for 21 days", "comparator": "Placebo in crossover", "endpoint": "Bilberry extract did not improve night visual acuity in the controlled healthy-young-men crossover trial.", "effect_direction": "no_detected_change", "combination": "single", "conditions": []} Explicit extracted experimental comparison; source-derived draft.
- experimental_model
- 15 men, 160 mg 25%-anthocyanoside bilberry extract three times daily, 21 days, washout/crossover.
- interpretation_status
- Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
- limitations
- Specific preparation and healthy population; not all eye diseases or all anthocyanin structures.
- plain_language
- Bilberry extract did not improve night visual acuity in the controlled healthy-young-men crossover trial.
- primary_references
- The effect of bilberry nutritional supplementation on night visual acuity and contrast sensitivity. | 2000 | PMID 10767671 | https://pubmed.ncbi.nlm.nih.gov/10767671/
- source_locator
- Reviewed reference lines 98-98; exact primary location described in quoted passage where extracted.
Anthocyanins: detailed mechanisms of action (reviewed 4 October 2026) · lines 98–98
Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · 15 men, 160 mg 25%-anthocyanoside bilberry extract three times daily, 21 days, washout/crossover. · source_derived_draft · unverified_draft
**Controlled human night-vision results were negative.** A 15-man crossover trial used 160 mg bilberry extract containing 25% anthocyanosides three times daily for 21 days, with a washout and crossover. Night visual acuity and contrast sensitivity did not improve versus placebo. This constrains that preparation in healthy young men; it is not a finding about all eye diseases. Wartime anecdotes are not substitutes for this comparison. [Muth et al., 2000](https://pubmed.ncbi.nlm.nih.gov/10767671/).
Complete structured claim and evidence
What acts on it
The specified preparation contains anthocyanins; its experimental effects remain attached to the actual preparation.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract reviewed; full methods, figures, exact doses or endpoint-specific species assignments may remain unextracted.
- experimental_model
- Preparation identity/scope; not isolated class causation.
- interpretation_status
- Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
- limitations
- A food or extract contains other constituents. Membership is a navigation link and does not transfer its findings to isolated anthocyanins.
- plain_language
- The specified preparation contains anthocyanins; its experimental effects remain attached to the actual preparation.
- primary_references
- The effect of bilberry nutritional supplementation on night visual acuity and contrast sensitivity. | 2000 | PMID 10767671 | https://pubmed.ncbi.nlm.nih.gov/10767671/
- source_locator
- Reviewed reference lines 98-98; exact primary location described in quoted passage where extracted.
Anthocyanins: detailed mechanisms of action (reviewed 4 October 2026) · lines 98–98
Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · Preparation identity/scope; not isolated class causation. · source_derived_draft · unverified_draft
**Controlled human night-vision results were negative.** A 15-man crossover trial used 160 mg bilberry extract containing 25% anthocyanosides three times daily for 21 days, with a washout and crossover. Night visual acuity and contrast sensitivity did not improve versus placebo. This constrains that preparation in healthy young men; it is not a finding about all eye diseases. Wartime anecdotes are not substitutes for this comparison. [Muth et al., 2000](https://pubmed.ncbi.nlm.nih.gov/10767671/).
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.