Component
Whole-body nitrogen balance
Whole-body nitrogen balance. Experimental scope belongs to the associated record.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Mean nitrogen balance was numerically higher with 10 mg/day B5 than without supplementation, but the between-group difference was not statistically significant.
Experimental context and source evidence
- cross_nutrient
- false
- evidence_location
- Primary PDF Table 1 visually checked; Tables 3–4 and Results pp.341–345.
- experimental_model
- Controlled 84-day feeding experiment in ten adult male inmates aged 27–33; six unsupplemented and four supplemented
- exposure
- Nine-week/63-day experimental diet essentially free of B5 versus 10 mg/day B5 as calcium pantothenate; both groups then received 100 mg/day for seven days.
- limitations
- Table 1 and the abstract distinguish unsupplemented and supplemented groups; one Methods sentence incorrectly says all received 10 mg. The table was visually checked. Historical assay and small cohort; the reported retention calculation is not direct measurement of intestinal absorption or tissue CoA. A numerical trend does not establish enhanced protein synthesis or an amino-acid repletion gate.
- nutrient_topic
- Pantothenic acid (vitamin B5) research collection; topical membership is not evidence of a direct dietary effect. · Pantothenate (vitamin B5)
- organism
- Homo sapiens
- plain_language
- This study did not demonstrate a significant improvement in nitrogen balance.
- primary_references
- [b5-clin-fry1976] Metabolic response to a pantothenic acid deficient diet in humans. (1976). https://pubmed.ncbi.nlm.nih.gov/1011047/ DOI: 10.3177/jnsv.22.339
- tissue_or_cell_type
- Urine and whole blood; nitrogen balance
Pantothenic acid (vitamin B5): coenzyme A, deficiency and nutrient interactions (2026-09-17) · lines 1271–1283
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Controlled 84-day feeding experiment in ten adult male inmates aged 27–33; six unsupplemented and four supplemented · source_derived_draft · unverified_draft
### b5-clin-nitrogen-not-significant Mean nitrogen balance was numerically higher with 10 mg/day B5 than without supplementation, but the between-group difference was not statistically significant. Condition category: normal nutrient_topic: Pantothenic acid (vitamin B5) research collection; topical membership is not evidence of a direct dietary effect. plain_language: This study did not demonstrate a significant improvement in nitrogen balance. organism: Homo sapiens tissue_or_cell_type: Urine and whole blood; nitrogen balance experimental_model: Controlled 84-day feeding experiment in ten adult male inmates aged 27–33; six unsupplemented and four supplemented limitations: Table 1 and the abstract distinguish unsupplemented and supplemented groups; one Methods sentence incorrectly says all received 10 mg. The table was visually checked. Historical assay and small cohort; the reported retention calculation is not direct measurement of intestinal absorption or tissue CoA. A numerical trend does not establish enhanced protein synthesis or an amino-acid repletion gate. exposure: Nine-week/63-day experimental diet essentially free of B5 versus 10 mg/day B5 as calcium pantothenate; both groups then received 100 mg/day for seven days. cross_nutrient: false evidence_location: Primary PDF Table 1 visually checked; Tables 3–4 and Results pp.341–345. [b5-clin-fry1976] Metabolic response to a pantothenic acid deficient diet in humans. (1976). https://pubmed.ncbi.nlm.nih.gov/1011047/ DOI: 10.3177/jnsv.22.339
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.