Component

Twenty-four-hour urinary iodine excretion

Twenty-four-hour urinary iodine excretion. Study-specific scope and measurement methods are recorded with each claim.

2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. The study estimated that 10 spot or 24-hour collections were needed to estimate individual iodine status with 20% precision in these women.

    Urinary iodine concentration → Twenty-four-hour urinary iodine excretion source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    biomarker_context Imported condition classification; unverified.
    cross_nutrient
    false
    evidence_location
    Primary indexed abstract.
    experimental_model
    Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77
    exposure
    341 24-hour urine collections and 177 corresponding fasting second-void morning spot samples; within-person variability used for precision estimates.
    limitations
    The sample-number estimate is specific to this population, sampling method and 20% precision target. It is not a universal instruction to collect ten specimens or a validated single-person diagnostic cutoff.
    nutrient_topic
    Iodine research collection; topical membership is not evidence of a direct dietary effect. · Iodine
    organism
    Homo sapiens
    plain_language
    The precision calculation required repeated samples, not a single diagnostic urine value.
    primary_references
    [iod-clin-konig2011] Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women. (2011). https://pubmed.ncbi.nlm.nih.gov/21918061/ DOI: 10.3945/jn.111.144071
    tissue_or_cell_type
    Spot and24-hour urine
    trigger_kind
    biomarker_context Imported condition classification; unverified.

    Iodine: thyroid hormone production, deficiency, excess and nutrient interactions (2026-09-17) · lines 1440–1452

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77 · source_derived_draft · unverified_draft

    ### iod-clin-urine-precision The study estimated that 10 spot or 24-hour collections were needed to estimate individual iodine status with 20% precision in these women. Condition category: biomarker_context nutrient_topic: Iodine research collection; topical membership is not evidence of a direct dietary effect. plain_language: The precision calculation required repeated samples, not a single diagnostic urine value. organism: Homo sapiens tissue_or_cell_type: Spot and24-hour urine experimental_model: Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77 limitations: The sample-number estimate is specific to this population, sampling method and 20% precision target. It is not a universal instruction to collect ten specimens or a validated single-person diagnostic cutoff. exposure: 341 24-hour urine collections and 177 corresponding fasting second-void morning spot samples; within-person variability used for precision estimates. cross_nutrient: false evidence_location: Primary indexed abstract. [iod-clin-konig2011] Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women. (2011). https://pubmed.ncbi.nlm.nih.gov/21918061/ DOI: 10.3945/jn.111.144071
    Complete structured claim and evidence

  2. Mean within-person variability was 32% for measured 24-hour iodine excretion, 33% for estimated 24-hour excretion and 38% for spot urinary iodine concentration.

    Urinary iodine concentration → Twenty-four-hour urinary iodine excretion source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    biomarker_context Imported condition classification; unverified.
    cross_nutrient
    false
    evidence_location
    Primary indexed abstract.
    experimental_model
    Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77
    exposure
    341 24-hour urine collections and 177 corresponding fasting second-void morning spot samples; within-person variability used for precision estimates.
    limitations
    The sample-number estimate is specific to this population, sampling method and 20% precision target. It is not a universal instruction to collect ten specimens or a validated single-person diagnostic cutoff.
    nutrient_topic
    Iodine research collection; topical membership is not evidence of a direct dietary effect. · Iodine
    organism
    Homo sapiens
    plain_language
    One urine result can vary substantially within the same person.
    primary_references
    [iod-clin-konig2011] Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women. (2011). https://pubmed.ncbi.nlm.nih.gov/21918061/ DOI: 10.3945/jn.111.144071
    tissue_or_cell_type
    Spot and24-hour urine
    trigger_kind
    biomarker_context Imported condition classification; unverified.

    Iodine: thyroid hormone production, deficiency, excess and nutrient interactions (2026-09-17) · lines 1426–1438

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77 · source_derived_draft · unverified_draft

    ### iod-clin-urine-variability Mean within-person variability was 32% for measured 24-hour iodine excretion, 33% for estimated 24-hour excretion and 38% for spot urinary iodine concentration. Condition category: biomarker_context nutrient_topic: Iodine research collection; topical membership is not evidence of a direct dietary effect. plain_language: One urine result can vary substantially within the same person. organism: Homo sapiens tissue_or_cell_type: Spot and24-hour urine experimental_model: Prospective 15-month repeated-collection study in 22 healthy Swiss women aged 52–77 limitations: The sample-number estimate is specific to this population, sampling method and 20% precision target. It is not a universal instruction to collect ten specimens or a validated single-person diagnostic cutoff. exposure: 341 24-hour urine collections and 177 corresponding fasting second-void morning spot samples; within-person variability used for precision estimates. cross_nutrient: false evidence_location: Primary indexed abstract. [iod-clin-konig2011] Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women. (2011). https://pubmed.ncbi.nlm.nih.gov/21918061/ DOI: 10.3945/jn.111.144071
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards