Component
Clinical response of ulcerative colitis in the specified trial
Clinical response of ulcerative colitis in the specified trial. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Clinical response occurred in 17/26 versus 3/24 participants.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/curcumin-research/25724700.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "470d55e94365249fc0b737c0b177188f2d4a968cd148b71c3ee6c621189cd09e", "start_char": 0, "end_char": 1945, "text_sha256": "470d55e94365249fc0b737c0b177188f2d4a968cd148b71c3ee6c621189cd09e"}
- experimental_model
- Multicenter randomized trial in 50 mesalamine-treated adults
- exposure
- Curcumin 3 g/day or placebo for one month with continuing mesalamine
- limitations
- Adjunctive treatment, not curcumin monotherapy. Small study and wide confidence intervals; molecular mediation not demonstrated.
- nutrient_topic
- Curcumin research collection; topical membership is not evidence of a direct dietary effect. · Curcumin
- organism
- Homo sapiens
- plain_language
- More participants also met the symptom-response criterion.
- primary_references
- [curcumin-p25724700] Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial. (2015). https://pubmed.ncbi.nlm.nih.gov/25724700/ DOI: 10.1016/j.cgh.2015.02.019
- tissue_or_cell_type
- Mild-to-moderate active ulcerative colitis
Curcumin: metabolism, signaling and nutrient connections (2026-09-17) · lines 1048–1059
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Multicenter randomized trial in 50 mesalamine-treated adults · source_derived_draft · unverified_draft
### curcumin-uc-response Clinical response occurred in 17/26 versus 3/24 participants. Condition category: normal nutrient_topic: Curcumin research collection; topical membership is not evidence of a direct dietary effect. plain_language: More participants also met the symptom-response criterion. organism: Homo sapiens tissue_or_cell_type: Mild-to-moderate active ulcerative colitis experimental_model: Multicenter randomized trial in 50 mesalamine-treated adults limitations: Adjunctive treatment, not curcumin monotherapy. Small study and wide confidence intervals; molecular mediation not demonstrated. exposure: Curcumin 3 g/day or placebo for one month with continuing mesalamine evidence_span: {"source_cache": "artifacts/curcumin-research/25724700.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "470d55e94365249fc0b737c0b177188f2d4a968cd148b71c3ee6c621189cd09e", "start_char": 0, "end_char": 1945, "text_sha256": "470d55e94365249fc0b737c0b177188f2d4a968cd148b71c3ee6c621189cd09e"} [curcumin-p25724700] Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial. (2015). https://pubmed.ncbi.nlm.nih.gov/25724700/ DOI: 10.1016/j.cgh.2015.02.019
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.