Component
Thyroid absorbed radiation dose from radioiodine
Study-specific endpoint; inspect claim context for model and measurement.
4 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
KI at +24 hours produced mean thyroid radiation-dose reduction of 2.8% in the timing comparison.
Experimental context and source evidence
- experimental_model
- 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- The timing of iodide delivery changed thyroid protection.
- primary_references
- Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 376–382
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft
## ki-block-24h The timing of iodide delivery changed thyroid protection. KI at +24 hours produced mean thyroid radiation-dose reduction of 2.8% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Complete structured claim and evidenceKI at +2 hours produced mean thyroid radiation-dose reduction of 59.7% in the timing comparison.
Experimental context and source evidence
- experimental_model
- 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- The timing of iodide delivery changed thyroid protection.
- primary_references
- Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 360–366
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft
## ki-block-2h The timing of iodide delivery changed thyroid protection. KI at +2 hours produced mean thyroid radiation-dose reduction of 59.7% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Complete structured claim and evidenceKI at +8 hours produced mean thyroid radiation-dose reduction of 25.4% in the timing comparison.
Experimental context and source evidence
- experimental_model
- 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- The timing of iodide delivery changed thyroid protection.
- primary_references
- Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 368–374
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft
## ki-block-8h The timing of iodide delivery changed thyroid protection. KI at +8 hours produced mean thyroid radiation-dose reduction of 25.4% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Complete structured claim and evidenceKI at −24 hours produced mean thyroid radiation-dose reduction of 88.7% in the timing comparison.
Experimental context and source evidence
- experimental_model
- 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
- exposure_category
- Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
- limitations
- Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
- nutrient_topic
- Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
- plain_language
- The timing of iodide delivery changed thyroid protection.
- primary_references
- Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 352–358
AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft
## ki-block-before The timing of iodide delivery changed thyroid protection. KI at −24 hours produced mean thyroid radiation-dose reduction of 88.7% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.