Component

Thyroid absorbed radiation dose from radioiodine

Study-specific endpoint; inspect claim context for model and measurement.

4 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. KI at +24 hours produced mean thyroid radiation-dose reduction of 2.8% in the timing comparison.

    Experimental context and source evidence
    experimental_model
    27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The timing of iodide delivery changed thyroid protection.
    primary_references
    Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 376–382

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft

    ## ki-block-24h The timing of iodide delivery changed thyroid protection. KI at +24 hours produced mean thyroid radiation-dose reduction of 2.8% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
    Complete structured claim and evidence
  2. KI at +2 hours produced mean thyroid radiation-dose reduction of 59.7% in the timing comparison.

    Experimental context and source evidence
    experimental_model
    27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The timing of iodide delivery changed thyroid protection.
    primary_references
    Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 360–366

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft

    ## ki-block-2h The timing of iodide delivery changed thyroid protection. KI at +2 hours produced mean thyroid radiation-dose reduction of 59.7% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
    Complete structured claim and evidence
  3. KI at +8 hours produced mean thyroid radiation-dose reduction of 25.4% in the timing comparison.

    Experimental context and source evidence
    experimental_model
    27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The timing of iodide delivery changed thyroid protection.
    primary_references
    Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 368–374

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft

    ## ki-block-8h The timing of iodide delivery changed thyroid protection. KI at +8 hours produced mean thyroid radiation-dose reduction of 25.4% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
    Complete structured claim and evidence
  4. KI at −24 hours produced mean thyroid radiation-dose reduction of 88.7% in the timing comparison.

    Experimental context and source evidence
    experimental_model
    27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine.
    exposure_category
    Study-specific exposure, including pharmacological and in-vitro conditions; normal is the schema fallback outside the three availability categories.
    limitations
    Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions.
    nutrient_topic
    Potassium iodide research collection; shared-anion and comparator studies are not all KI interventions. · Potassium iodide
    plain_language
    The timing of iodide delivery changed thyroid protection.
    primary_references
    Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539

    Potassium iodide: thyroid and non-thyroid mechanisms, interactions and discovery questions (2026-09-18) · lines 352–358

    AI-assisted research curation; primary-study references, chemical references and label statements individually identified. Not publisher full text. · supports · 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. · source_derived_draft · unverified_draft

    ## ki-block-before The timing of iodide delivery changed thyroid protection. KI at −24 hours produced mean thyroid radiation-dose reduction of 88.7% in the timing comparison. Model: 27 healthy adults, 48 paired kinetic assessments; 100 mg KI at specified times relative to radioiodine. Limitations: Tracer/dosimetry study, not cancer outcomes; timings are experimental, not personal instructions. Evidence location: Primary abstract Facing the nuclear threat: thyroid blocking revisited. · 2011 · https://pubmed.ncbi.nlm.nih.gov/21865356/ · DOI 10.1210/jc.2011-1539
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards