Component
Subjective headache rating
Subjective headache rating. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Theanine alone increased headache ratings in the acute experiment.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/theanine-research/18006208.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "387d341f5aec1fb42bed06021ceb14cc8b49bfdf0f5502284a98806ca732cbdf", "start_char": 0, "end_char": 1386, "text_sha256": "387d341f5aec1fb42bed06021ceb14cc8b49bfdf0f5502284a98806ca732cbdf"}
- experimental_model
- Randomized double-blind balanced crossover experiment
- exposure
- 250 mg theanine, 150 mg caffeine, combination and placebo
- limitations
- Acute effects depend on task and treatment. Benefits of the mixture do not establish synergy for all outcomes or neutralization of caffeine.
- nutrient_topic
- L-Theanine research collection; topical membership is not evidence of a direct dietary effect. · L-Theanine
- organism
- Healthy adults
- plain_language
- Unfavorable findings remain visible alongside potential benefits.
- primary_references
- [theanine-p18006208] The effects of L-theanine, caffeine and their combination on cognition and mood. (2008). https://pubmed.ncbi.nlm.nih.gov/18006208/ DOI: 10.1016/j.biopsycho.2007.09.008
- tissue_or_cell_type
- Cognition and subjective state
L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17) · lines 965–976
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind balanced crossover experiment · source_derived_draft · unverified_draft
### theanine-theanine-headache Theanine alone increased headache ratings in the acute experiment. Condition category: normal nutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect. plain_language: Unfavorable findings remain visible alongside potential benefits. organism: Healthy adults tissue_or_cell_type: Cognition and subjective state experimental_model: Randomized double-blind balanced crossover experiment limitations: Acute effects depend on task and treatment. Benefits of the mixture do not establish synergy for all outcomes or neutralization of caffeine. exposure: 250 mg theanine, 150 mg caffeine, combination and placebo evidence_span: {"source_cache": "artifacts/theanine-research/18006208.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "387d341f5aec1fb42bed06021ceb14cc8b49bfdf0f5502284a98806ca732cbdf", "start_char": 0, "end_char": 1386, "text_sha256": "387d341f5aec1fb42bed06021ceb14cc8b49bfdf0f5502284a98806ca732cbdf"} [theanine-p18006208] The effects of L-theanine, caffeine and their combination on cognition and mood. (2008). https://pubmed.ncbi.nlm.nih.gov/18006208/ DOI: 10.1016/j.biopsycho.2007.09.008
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.