Component
Serum administered parent calciferol concentration
Study-defined Serum administered parent calciferol concentration. Read each linked record for species, exposure and endpoint.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The administered D2 and D3 produced similar initial rises in their respective parent calciferol serum concentrations.
Experimental context and source evidence
- cross_nutrient
- false
- experimental_model
- Human single-dose comparison; 20 healthy men; 28-day follow-up
- exposure
- One oral 50, 000-IU dose of D2 or D3; serial serum measures for 28 days.
- limitations
- Single 50, 000-IU dose in healthy men; biochemical response, not fracture efficacy. Model-extrapolated potency is not a universal IU conversion.
- nutrient_topic
- Vitamin D2 and D3 research collection; topical membership is not evidence of a direct dietary effect. · Vitamin D2 and D3
- organism
- Homo sapiens
- plain_language
- The two forms entered the circulation similarly in this single-dose experiment.
- primary_references
- [armas2004] Vitamin D2 is much less effective than vitamin D3 in humans. (2004). https://pubmed.ncbi.nlm.nih.gov/15531486/ DOI: 10.1210/jc.2004-0360
- tissue_or_cell_type
- Human circulating measurements
Vitamin D2 and D3: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1223–1234
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Human single-dose comparison; 20 healthy men; 28-day follow-up · source_derived_draft · unverified_draft
### vd-armas-parent-appearance The administered D2 and D3 produced similar initial rises in their respective parent calciferol serum concentrations. Condition category: normal nutrient_topic: Vitamin D2 and D3 research collection; topical membership is not evidence of a direct dietary effect. plain_language: The two forms entered the circulation similarly in this single-dose experiment. organism: Homo sapiens tissue_or_cell_type: Human circulating measurements experimental_model: Human single-dose comparison; 20 healthy men; 28-day follow-up limitations: Single 50, 000-IU dose in healthy men; biochemical response, not fracture efficacy. Model-extrapolated potency is not a universal IU conversion. exposure: One oral 50, 000-IU dose of D2 or D3; serial serum measures for 28 days. cross_nutrient: false [armas2004] Vitamin D2 is much less effective than vitamin D3 in humans. (2004). https://pubmed.ncbi.nlm.nih.gov/15531486/ DOI: 10.1210/jc.2004-0360
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.