Component

Rat plasma melatonin concentration

Rat plasma melatonin concentration. Species, exposure and limitations are retained in each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Mean plasma melatonin was about 50 versus 75 pg/mL in magnesium-deficient versus adequate-diet rats.

    Magnesium → Rat plasma melatonin concentration source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    nutrient_deficiency Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/melatonin-research/17172005.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "32a85d5fa095aeb2258c9ee44e480deb8c3292aafc9bd13edb4172d1743caf50", "start_char": 0, "end_char": 969, "text_sha256": "32a85d5fa095aeb2258c9ee44e480deb8c3292aafc9bd13edb4172d1743caf50"}
    experimental_model
    Controlled dietary magnesium-deficiency pilot
    exposure
    150 versus 1000 ppm magnesium diet for four weeks
    limitations
    Animal dietary exposure; enzyme mechanism was not established by this experiment. No human intake threshold or universal repletion-failure rule can be derived.
    nutrient_topic
    Melatonin research collection; topical membership is not evidence of a direct dietary effect. · Melatonin
    organism
    Male Sprague-Dawley rats
    plain_language
    A nutrient shortage altered the measured hormone level in an animal experiment.
    primary_references
    [melatonin-p17172005] Dietary magnesium deficiency decreases plasma melatonin in rats. (2006). https://pubmed.ncbi.nlm.nih.gov/17172005/
    tissue_or_cell_type
    Dark-phase plasma melatonin
    trigger_kind
    nutrient_deficiency Imported condition classification; unverified.

    Melatonin: synthesis, receptors, circadian timing and nutrient interactions (2026-09-17) · lines 760–771

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Controlled dietary magnesium-deficiency pilot · source_derived_draft · unverified_draft

    ### melatonin-magnesium-low-melatonin Mean plasma melatonin was about 50 versus 75 pg/mL in magnesium-deficient versus adequate-diet rats. Condition category: nutrient_deficiency nutrient_topic: Melatonin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A nutrient shortage altered the measured hormone level in an animal experiment. organism: Male Sprague-Dawley rats tissue_or_cell_type: Dark-phase plasma melatonin experimental_model: Controlled dietary magnesium-deficiency pilot limitations: Animal dietary exposure; enzyme mechanism was not established by this experiment. No human intake threshold or universal repletion-failure rule can be derived. exposure: 150 versus 1000 ppm magnesium diet for four weeks evidence_span: {"source_cache": "artifacts/melatonin-research/17172005.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "32a85d5fa095aeb2258c9ee44e480deb8c3292aafc9bd13edb4172d1743caf50", "start_char": 0, "end_char": 969, "text_sha256": "32a85d5fa095aeb2258c9ee44e480deb8c3292aafc9bd13edb4172d1743caf50"} [melatonin-p17172005] Dietary magnesium deficiency decreases plasma melatonin in rats. (2006). https://pubmed.ncbi.nlm.nih.gov/17172005/
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards