Component

Potassium gluconate

Independent biological entity. Read linked claims for experimental scope and context.

4 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. Urinary potassium recovery was greater after potato intake than after the supplement despite no detected source difference in serum exposure.

    Potassium gluconate → Urinary potassium excretion source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Same feeding study.
    limitations
    Urinary potassium alone is not an exact measure of food intake or intracellular stores.
    nutrient_topic
    Potassium research collection; topical membership is not evidence of a direct dietary effect. · Potassium
    organism
    Homo sapiens
    plain_language
    Urinary recovery and absorption are related but distinct measurements.
    primary_references
    [k-macdonald2016] Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial (2016). https://pubmed.ncbi.nlm.nih.gov/27413123/ DOI: 10.3945/ajcn.115.127225
    tissue_or_cell_type
    Urine and serum

    Potassium: cross-nutrient mechanisms and deficiency (2026-09-17) · lines 1464–1473

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Same feeding study. · source_derived_draft · unverified_draft

    ### k-potato-urinary-recovery Urinary potassium recovery was greater after potato intake than after the supplement despite no detected source difference in serum exposure. Condition category: normal nutrient_topic: Potassium research collection; topical membership is not evidence of a direct dietary effect. plain_language: Urinary recovery and absorption are related but distinct measurements. organism: Homo sapiens tissue_or_cell_type: Urine and serum experimental_model: Same feeding study. limitations: Urinary potassium alone is not an exact measure of food intake or intracellular stores. [k-macdonald2016] Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial (2016). https://pubmed.ncbi.nlm.nih.gov/27413123/ DOI: 10.3945/ajcn.115.127225
    Complete structured claim and evidence

Where it participates (unsigned role)

  1. Bicarbonate salts and potassium gluconate increased bicarbonate in the CKD crossover; urinary citrate rose and ammonium fell.

    Potassium bicarbonate → Plasma bicarbonate concentration source_derived_draftungraded
    Experimental context and source evidence
    cross_nutrient
    Salt anion -> bicarbonate/citrate/ammonium.
    experimental_model
    31 participants; five-day randomized periods.
    limitations
    Short exposure and washout; unchanged diet advised rather than controlled.
    nutrient_topic
    Potassium research collection; topical membership is not evidence of a direct dietary effect. · Potassium
    organism
    Homo sapiens
    plain_language
    The accompanying anion changed the acid-base response.
    primary_references
    [k-ckd-salts2026] Randomized Cross-Over Trial of Electrolyte, Acid-Base and Blood Pressure Effects of Salt Supplements in CKD (2026). https://pubmed.ncbi.nlm.nih.gov/42381762/ DOI: 10.1016/j.ekir.2026.106619
    tissue_or_cell_type
    Plasma and urine

    Potassium: cross-nutrient mechanisms and deficiency (2026-09-17) · lines 1662–1672

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · 31 participants; five-day randomized periods. · source_derived_draft · unverified_draft

    ### k-ckd-salts-alkalizing-comparison Bicarbonate salts and potassium gluconate increased bicarbonate in the CKD crossover; urinary citrate rose and ammonium fell. Condition category: normal nutrient_topic: Potassium research collection; topical membership is not evidence of a direct dietary effect. plain_language: The accompanying anion changed the acid-base response. organism: Homo sapiens tissue_or_cell_type: Plasma and urine experimental_model: 31 participants; five-day randomized periods. limitations: Short exposure and washout; unchanged diet advised rather than controlled. cross_nutrient: Salt anion -> bicarbonate/citrate/ammonium. [k-ckd-salts2026] Randomized Cross-Over Trial of Electrolyte, Acid-Base and Blood Pressure Effects of Salt Supplements in CKD (2026). https://pubmed.ncbi.nlm.nih.gov/42381762/ DOI: 10.1016/j.ekir.2026.106619
    Complete structured claim and evidence

  2. All three potassium salts increased plasma potassium despite their different acid-base effects.

    Potassium ion → Plasma potassium concentration source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Same CKD crossover.
    limitations
    Cannot infer long-term food effects.
    nutrient_topic
    Potassium research collection; topical membership is not evidence of a direct dietary effect. · Potassium
    organism
    Homo sapiens
    plain_language
    An alkalizing potassium salt did not remove the potassium rise in this study.
    primary_references
    [k-ckd-salts2026] Randomized Cross-Over Trial of Electrolyte, Acid-Base and Blood Pressure Effects of Salt Supplements in CKD (2026). https://pubmed.ncbi.nlm.nih.gov/42381762/ DOI: 10.1016/j.ekir.2026.106619
    tissue_or_cell_type
    Plasma

    Potassium: cross-nutrient mechanisms and deficiency (2026-09-17) · lines 1674–1683

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Same CKD crossover. · source_derived_draft · unverified_draft

    ### k-ckd-salts-potassium-not-rescued-by-alkali All three potassium salts increased plasma potassium despite their different acid-base effects. Condition category: normal nutrient_topic: Potassium research collection; topical membership is not evidence of a direct dietary effect. plain_language: An alkalizing potassium salt did not remove the potassium rise in this study. organism: Homo sapiens tissue_or_cell_type: Plasma experimental_model: Same CKD crossover. limitations: Cannot infer long-term food effects. [k-ckd-salts2026] Randomized Cross-Over Trial of Electrolyte, Acid-Base and Blood Pressure Effects of Salt Supplements in CKD (2026). https://pubmed.ncbi.nlm.nih.gov/42381762/ DOI: 10.1016/j.ekir.2026.106619
    Complete structured claim and evidence

  3. Modeled potassium absorption was high and not detectably different between potatoes and gluconate in the short feeding comparison.

    Potassium → Intestinal potassium absorption source_derived_draftungraded
    Experimental context and source evidence
    experimental_model
    Five-day feeding periods.
    exposure
    Added 20, 40 or 60 mEq/day; fries evaluated separately.
    limitations
    Specific foods and healthy participants; does not rank all foods or establish long-term outcomes.
    nutrient_topic
    Potassium research collection; topical membership is not evidence of a direct dietary effect. · Potassium
    organism
    Homo sapiens
    plain_language
    Potassium in the tested food and salt both reached the body.
    primary_references
    [k-macdonald2016] Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial (2016). https://pubmed.ncbi.nlm.nih.gov/27413123/ DOI: 10.3945/ajcn.115.127225
    tissue_or_cell_type
    Gastrointestinal tract; modeled balance

    Potassium: cross-nutrient mechanisms and deficiency (2026-09-17) · lines 1452–1462

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Five-day feeding periods. · source_derived_draft · unverified_draft

    ### k-potato-gluconate-absorption Modeled potassium absorption was high and not detectably different between potatoes and gluconate in the short feeding comparison. Condition category: normal nutrient_topic: Potassium research collection; topical membership is not evidence of a direct dietary effect. plain_language: Potassium in the tested food and salt both reached the body. organism: Homo sapiens tissue_or_cell_type: Gastrointestinal tract; modeled balance experimental_model: Five-day feeding periods. limitations: Specific foods and healthy participants; does not rank all foods or establish long-term outcomes. exposure: Added 20, 40 or 60 mEq/day; fries evaluated separately. [k-macdonald2016] Bioavailability of potassium from potatoes and potassium gluconate: a randomized dose response trial (2016). https://pubmed.ncbi.nlm.nih.gov/27413123/ DOI: 10.3945/ajcn.115.127225
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards