Component
Mouse TRPV3
Context-specific entity; species, compartment and exposure are stated on each claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
TRPV3 mediated strontium influx into mouse eggs in the reported channel and activation experiments.
Experimental context and source evidence
- evidence_access
- Primary full text
- experimental_model
- Mouse egg electrophysiology and genetic experiments.
- limitations
- Laboratory artificial activation; no claim about dietary strontium or human fertility.
- nutrient_topic
- Strontium collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Strontium
- plain_language
- A calcium-permeable channel can also admit strontium in mouse eggs.
- primary_references
- TRPV3 channels mediate strontium-induced mouse-egg activation. · 2013 · https://pubmed.ncbi.nlm.nih.gov/24316078/ · DOI 10.1016/j.celrep.2013.11.007
Strontium: calcium interactions, cellular mechanisms and mineralization (2026-09-19) · lines 382–388
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Mouse egg electrophysiology and genetic experiments. · source_derived_draft · unverified_draft
## strontium-mouse-egg-entry A calcium-permeable channel can also admit strontium in mouse eggs. TRPV3 mediated strontium influx into mouse eggs in the reported channel and activation experiments. Model: Mouse egg electrophysiology and genetic experiments. Limitations: Laboratory artificial activation; no claim about dietary strontium or human fertility. Evidence access: Primary full text TRPV3 channels mediate strontium-induced mouse-egg activation. · 2013 · https://pubmed.ncbi.nlm.nih.gov/24316078/ · DOI 10.1016/j.celrep.2013.11.007
Complete structured claim and evidenceTrpv3-knockout mouse eggs failed to conduct Sr2+ or undergo strontium-induced activation.
Experimental context and source evidence
- availability_state
- machinery_impairment Imported condition classification; unverified.
- evidence_access
- Primary full text
- experimental_model
- Mouse Trpv3 genetic knockout.
- limitations
- Does not establish that channel expression alone is sufficient in other species.
- nutrient_topic
- Strontium collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Strontium
- plain_language
- Removing the channel removes the experimental response.
- primary_references
- TRPV3 channels mediate strontium-induced mouse-egg activation. · 2013 · https://pubmed.ncbi.nlm.nih.gov/24316078/ · DOI 10.1016/j.celrep.2013.11.007
- trigger_kind
- machinery_impairment Imported condition classification; unverified.
Strontium: calcium interactions, cellular mechanisms and mineralization (2026-09-19) · lines 390–396
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Mouse Trpv3 genetic knockout. · source_derived_draft · unverified_draft
## strontium-mouse-trpv3-loss Removing the channel removes the experimental response. Trpv3-knockout mouse eggs failed to conduct Sr2+ or undergo strontium-induced activation. Model: Mouse Trpv3 genetic knockout. Limitations: Does not establish that channel expression alone is sufficient in other species. Evidence access: Primary full text TRPV3 channels mediate strontium-induced mouse-egg activation. · 2013 · https://pubmed.ncbi.nlm.nih.gov/24316078/ · DOI 10.1016/j.celrep.2013.11.007
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.