Component
Mouse liver CoQ10 after acute red yeast rice gavage
Context-specific entity; species, compartment and exposure are stated on each claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Acute red yeast rice gavage at 1 or 5 g/kg reduced hepatic CoQ10 in male ICR mice, with suppression still reported at 24 hours.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_access
- Primary abstract
- experimental_model
- Soybean-oil preparation; eight mice per experimental subgroup, sampled from 0.5 to 24 hours.
- limitations
- High-dose rodent exposure; the abstract describes controls killed immediately, so time and feeding controls limit interpretation. No human dose equivalence is inferred.
- nutrient_topic
- Red yeast rice collection; species, compartment, exposure, co-substrates and manipulation remain explicit. · Red yeast rice
- plain_language
- The mixture itself was tested in mice at high doses.
- primary_references
- [15705235] Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR mice. · 2005 · https://pubmed.ncbi.nlm.nih.gov/15705235/ · DOI 10.1079/bjn20041285
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Red yeast rice: constituents, mevalonate, CoQ and product-specific interactions (2026-09-20) · lines 92–98
AI-assisted research curation; primary references, access levels and experimental limitations individually identified. Not publisher full text. · supports · Soybean-oil preparation; eight mice per experimental subgroup, sampled from 0.5 to 24 hours. · source_derived_draft · unverified_draft
## red-yeast-rice-mouse-ryr-liver-coq The mixture itself was tested in mice at high doses. Acute red yeast rice gavage at 1 or 5 g/kg reduced hepatic CoQ10 in male ICR mice, with suppression still reported at 24 hours. Model: Soybean-oil preparation; eight mice per experimental subgroup, sampled from 0.5 to 24 hours. Limitations: High-dose rodent exposure; the abstract describes controls killed immediately, so time and feeding controls limit interpretation. No human dose equivalence is inferred. Evidence access: Primary abstract [15705235] Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR mice. · 2005 · https://pubmed.ncbi.nlm.nih.gov/15705235/ · DOI 10.1079/bjn20041285
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.