Component
Infant weight gain
Infant weight gain. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Both infants resumed normal weight gain after switching to a formula with adequate chloride.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/chloride-research/7354566.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3b7b6f5d5a9768b20ea47cf913f35928464109148730676363c19c4ba39fb2c4", "start_char": 0, "end_char": 418, "text_sha256": "3b7b6f5d5a9768b20ea47cf913f35928464109148730676363c19c4ba39fb2c4"}
- experimental_model
- Two infant cases after a formula manufacturing error
- exposure
- Severely chloride-deficient soy formula replaced
- limitations
- Case reports; not a population prevalence estimate.
- nutrient_topic
- Chloride research collection; topical membership is not evidence of a direct dietary effect. · Chloride
- organism
- Human
- plain_language
- Correcting the feeding problem restored growth in these cases.
- primary_references
- [chloride-p7354566] Failure to thrive and metabolic alkalosis. Adverse effects of a chloride-deficient formula in two infants. (1980). https://pubmed.ncbi.nlm.nih.gov/7354566/ DOI: 10.1001/jama.1980.03300360040024
- tissue_or_cell_type
- Nutrition and growth
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Chloride: transport, acid-base balance, nutrient interactions and loss states (2026-09-17) · lines 822–833
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Two infant cases after a formula manufacturing error · source_derived_draft · unverified_draft
### chloride-formula-growth Both infants resumed normal weight gain after switching to a formula with adequate chloride. Condition category: nutrient_deficiency nutrient_topic: Chloride research collection; topical membership is not evidence of a direct dietary effect. plain_language: Correcting the feeding problem restored growth in these cases. organism: Human tissue_or_cell_type: Nutrition and growth experimental_model: Two infant cases after a formula manufacturing error limitations: Case reports; not a population prevalence estimate. exposure: Severely chloride-deficient soy formula replaced evidence_span: {"source_cache": "artifacts/chloride-research/7354566.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3b7b6f5d5a9768b20ea47cf913f35928464109148730676363c19c4ba39fb2c4", "start_char": 0, "end_char": 418, "text_sha256": "3b7b6f5d5a9768b20ea47cf913f35928464109148730676363c19c4ba39fb2c4"} [chloride-p7354566] Failure to thrive and metabolic alkalosis. Adverse effects of a chloride-deficient formula in two infants. (1980). https://pubmed.ncbi.nlm.nih.gov/7354566/ DOI: 10.1001/jama.1980.03300360040024
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.