Component
Human blood glucose response to sucrose challenge
Species, exposure, manipulation and limitations are specified on each linked claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Acarbose 200 mg reduced blood-glucose response area by 89% after a 50 g sucrose load in healthy volunteers.
Experimental context and source evidence
- availability_state
- machinery_impairment Imported condition classification; unverified.
- dose
- 50 g carbohydrate load; 200 or 50 mg acarbose
- duration
- Acute tolerance tests; exact sampling duration unrecovered
- evidence_access
- Primary abstract/metadata; unrecovered methods explicitly retained.
- evidence_scope
- literature_reviewed; source-specific curation
- experimental_model
- Healthy human volunteers; sample size unavailable in accessed abstract
- exposure_scope
- Drug and nutrient interaction
- limitations
- Acarbose inhibits carbohydrate hydrolysis. The glucose-only comparison does not support direct blockade of glucose transport. Experimental doses are not a dosing recommendation.
- nutrient_topic
- Sucrose chapter; direct sucrose observations are distinguished from shared component metabolism. · Sucrose
- organism
- Healthy human volunteers; sample size unavailable in accessed abstract
- plain_language
- Acarbose 200 mg reduced blood-glucose response area by 89% after a 50 g sucrose load in healthy volunteers.
- primary_references
- Scope and specificity of acarbose in slowing carbohydrate absorption in man. (1981). https://pubmed.ncbi.nlm.nih.gov/7028548/ DOI: 10.2337/diab.30.11.951
- route
- Oral carbohydrate and drug
- tissue
- Carbohydrate tolerance and breath hydrogen
- trigger_kind
- machinery_impairment Imported condition classification; unverified.
Sucrose: mechanism of action and metabolic impact (2026-09-20) · lines 199–209
Original AI-assisted source-specific sucrose curation with shared canonical claims retained by identity. Primary-study citations, negative findings, exposure details and limitations preserved. Not publisher full text. · supports · Healthy human volunteers; sample size unavailable in accessed abstract · source_derived_draft · unverified_draft
## sucrose-acarbose-glycemia Acarbose 200 mg reduced blood-glucose response area by 89% after a 50 g sucrose load in healthy volunteers. Model/species: Healthy human volunteers; sample size unavailable in accessed abstract Tissue: Carbohydrate tolerance and breath hydrogen Exposure: 50 g carbohydrate load; 200 or 50 mg acarbose Route: Oral carbohydrate and drug Duration: Acute tolerance tests; exact sampling duration unrecovered Exposure scope: Drug and nutrient interaction Limits: Acarbose inhibits carbohydrate hydrolysis. The glucose-only comparison does not support direct blockade of glucose transport. Experimental doses are not a dosing recommendation. Reference: Scope and specificity of acarbose in slowing carbohydrate absorption in man. (1981). https://pubmed.ncbi.nlm.nih.gov/7028548/ DOI: 10.2337/diab.30.11.951 Access: Primary abstract/metadata; unrecovered methods explicitly retained.
Complete structured claim and evidenceAcarbose 50 mg still reduced the blood-glucose response to sucrose, without a significant breath-hydrogen increase.
Experimental context and source evidence
- availability_state
- machinery_impairment Imported condition classification; unverified.
- dose
- 50 g carbohydrate load; 200 or 50 mg acarbose
- duration
- Acute tolerance tests; exact sampling duration unrecovered
- evidence_access
- Primary abstract/metadata; unrecovered methods explicitly retained.
- evidence_scope
- literature_reviewed; source-specific curation
- experimental_model
- Healthy human volunteers; sample size unavailable in accessed abstract
- exposure_scope
- Drug and nutrient interaction
- limitations
- Acarbose inhibits carbohydrate hydrolysis. The glucose-only comparison does not support direct blockade of glucose transport. Experimental doses are not a dosing recommendation.
- nutrient_topic
- Sucrose chapter; direct sucrose observations are distinguished from shared component metabolism. · Sucrose
- organism
- Healthy human volunteers; sample size unavailable in accessed abstract
- plain_language
- Acarbose 50 mg still reduced the blood-glucose response to sucrose, without a significant breath-hydrogen increase.
- primary_references
- Scope and specificity of acarbose in slowing carbohydrate absorption in man. (1981). https://pubmed.ncbi.nlm.nih.gov/7028548/ DOI: 10.2337/diab.30.11.951
- route
- Oral carbohydrate and drug
- tissue
- Carbohydrate tolerance and breath hydrogen
- trigger_kind
- machinery_impairment Imported condition classification; unverified.
Sucrose: mechanism of action and metabolic impact (2026-09-20) · lines 235–245
Original AI-assisted source-specific sucrose curation with shared canonical claims retained by identity. Primary-study citations, negative findings, exposure details and limitations preserved. Not publisher full text. · supports · Healthy human volunteers; sample size unavailable in accessed abstract · source_derived_draft · unverified_draft
## sucrose-acarbose-low-dose Acarbose 50 mg still reduced the blood-glucose response to sucrose, without a significant breath-hydrogen increase. Model/species: Healthy human volunteers; sample size unavailable in accessed abstract Tissue: Carbohydrate tolerance and breath hydrogen Exposure: 50 g carbohydrate load; 200 or 50 mg acarbose Route: Oral carbohydrate and drug Duration: Acute tolerance tests; exact sampling duration unrecovered Exposure scope: Drug and nutrient interaction Limits: Acarbose inhibits carbohydrate hydrolysis. The glucose-only comparison does not support direct blockade of glucose transport. Experimental doses are not a dosing recommendation. Reference: Scope and specificity of acarbose in slowing carbohydrate absorption in man. (1981). https://pubmed.ncbi.nlm.nih.gov/7028548/ DOI: 10.2337/diab.30.11.951 Access: Primary abstract/metadata; unrecovered methods explicitly retained.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.