Component
Human milk riboflavin concentration
Measured process or biological entity; consult each linked claim for the experimental scope.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Infants of supplemented mothers had lower activation coefficients; maternal and infant values rose toward placebo levels after supplement withdrawal.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- experimental_model
- Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants.
- exposure
- Maternal 2 mg/day riboflavin or placebo for 12 weeks; background intake about 0.5 mg/day; supplementation-withdrawal observations.
- limitations
- Supports maternal-infant supply responsiveness; not proof of a developmental benefit or an independently measured transport mechanism.
- nutrient_topic
- Riboflavin research collection; topical membership is not evidence of a direct dietary effect. · Riboflavin (vitamin B2)
- organism
- Homo sapiens
- plain_language
- The infant marker improved while maternal B2 was supplied and worsened again after it stopped.
- primary_references
- [b2-bates1982] Riboflavin requirements of lactating Gambian women: a controlled supplementation trial (1982). https://pubmed.ncbi.nlm.nih.gov/7072623/ DOI: 10.1093/ajcn/35.4.701
- tissue_or_cell_type
- Infant erythrocytes in maternal lactation trial
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Riboflavin: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1777–1787
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants. · source_derived_draft · unverified_draft
### b2-milk-infant-marker-response Infants of supplemented mothers had lower activation coefficients; maternal and infant values rose toward placebo levels after supplement withdrawal. Condition category: nutrient_deficiency nutrient_topic: Riboflavin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The infant marker improved while maternal B2 was supplied and worsened again after it stopped. organism: Homo sapiens tissue_or_cell_type: Infant erythrocytes in maternal lactation trial experimental_model: Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants. limitations: Supports maternal-infant supply responsiveness; not proof of a developmental benefit or an independently measured transport mechanism. exposure: Maternal 2 mg/day riboflavin or placebo for 12 weeks; background intake about 0.5 mg/day; supplementation-withdrawal observations. [b2-bates1982] Riboflavin requirements of lactating Gambian women: a controlled supplementation trial (1982). https://pubmed.ncbi.nlm.nih.gov/7072623/ DOI: 10.1093/ajcn/35.4.701
Complete structured claim and evidence
What acts on it
Maternal supplementation increased breast-milk riboflavin and improved maternal status compared with placebo in the Gambian lactation trial.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- experimental_model
- Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants.
- exposure
- Maternal 2 mg/day riboflavin or placebo for 12 weeks; background intake about 0.5 mg/day; supplementation-withdrawal observations.
- limitations
- Nutritionally constrained population; no direct mammary transporter assay in this trial.
- nutrient_topic
- Riboflavin research collection; topical membership is not evidence of a direct dietary effect. · Riboflavin (vitamin B2)
- organism
- Homo sapiens
- plain_language
- The mother’s B2 supply affected the vitamin delivered in milk.
- primary_references
- [b2-bates1982] Riboflavin requirements of lactating Gambian women: a controlled supplementation trial (1982). https://pubmed.ncbi.nlm.nih.gov/7072623/ DOI: 10.1093/ajcn/35.4.701
- tissue_or_cell_type
- Maternal blood and human milk
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Riboflavin: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 1765–1775
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants. · source_derived_draft · unverified_draft
### b2-maternal-milk-response Maternal supplementation increased breast-milk riboflavin and improved maternal status compared with placebo in the Gambian lactation trial. Condition category: nutrient_deficiency nutrient_topic: Riboflavin research collection; topical membership is not evidence of a direct dietary effect. plain_language: The mother’s B2 supply affected the vitamin delivered in milk. organism: Homo sapiens tissue_or_cell_type: Maternal blood and human milk experimental_model: Double-blind controlled trial in 60 lactating women from two Gambian villages and their infants. limitations: Nutritionally constrained population; no direct mammary transporter assay in this trial. exposure: Maternal 2 mg/day riboflavin or placebo for 12 weeks; background intake about 0.5 mg/day; supplementation-withdrawal observations. [b2-bates1982] Riboflavin requirements of lactating Gambian women: a controlled supplementation trial (1982). https://pubmed.ncbi.nlm.nih.gov/7072623/ DOI: 10.1093/ajcn/35.4.701
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.