Component
Human circulating taurine across age
Context-specific entity; species, compartment and exposure are stated on each claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The 2023 study reported lower circulating taurine with age in its human samples, alongside corresponding age comparisons in mice and monkeys.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_access
- Primary abstract
- experimental_model
- Human age-group observations; separate animal datasets.
- limitations
- Association alone does not establish deficiency as a cause or specify a universal threshold.
- nutrient_topic
- Taurine collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Taurine
- plain_language
- The original aging paper reported a fall in blood taurine.
- primary_references
- Taurine deficiency as a driver of aging. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37289866/ · DOI 10.1126/science.abn9257
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Taurine: synthesis, transport, mitochondrial decoding and nutrient interactions (2026-09-19) · lines 569–575
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Human age-group observations; separate animal datasets. · source_derived_draft · unverified_draft
## taurine-aging-decline The original aging paper reported a fall in blood taurine. The 2023 study reported lower circulating taurine with age in its human samples, alongside corresponding age comparisons in mice and monkeys. Model: Human age-group observations; separate animal datasets. Limitations: Association alone does not establish deficiency as a cause or specify a universal threshold. Evidence access: Primary abstract Taurine deficiency as a driver of aging. · 2023 · https://pubmed.ncbi.nlm.nih.gov/37289866/ · DOI 10.1126/science.abn9257
Complete structured claim and evidenceThe 2025 study found circulating taurine increased or remained unchanged with age in three geographically distinct human cohorts, with longitudinal and cross-sectional analyses and supporting nonhuman datasets.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_access
- Primary abstract
- experimental_model
- Human cohorts plus nonhuman primates and mice; repeated and cross-sectional measurements.
- limitations
- A biomarker challenge does not by itself refute every animal supplementation outcome.
- nutrient_topic
- Taurine collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Taurine
- plain_language
- Later data did not reproduce a consistent age-related decline.
- primary_references
- Is taurine an aging biomarker? · 2025 · https://pubmed.ncbi.nlm.nih.gov/40472098/ · DOI 10.1126/science.adl2116
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Taurine: synthesis, transport, mitochondrial decoding and nutrient interactions (2026-09-19) · lines 577–583
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Human cohorts plus nonhuman primates and mice; repeated and cross-sectional measurements. · source_derived_draft · unverified_draft
## taurine-aging-not-universal Later data did not reproduce a consistent age-related decline. The 2025 study found circulating taurine increased or remained unchanged with age in three geographically distinct human cohorts, with longitudinal and cross-sectional analyses and supporting nonhuman datasets. Model: Human cohorts plus nonhuman primates and mice; repeated and cross-sectional measurements. Limitations: A biomarker challenge does not by itself refute every animal supplementation outcome. Evidence access: Primary abstract Is taurine an aging biomarker? · 2025 · https://pubmed.ncbi.nlm.nih.gov/40472098/ · DOI 10.1126/science.adl2116
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.