Component
Baseline microbial glucosinolate-operon abundance
Baseline microbial glucosinolate-operon abundance. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Baseline abundance of the bacterial glucosinolate-conversion operon correlated with serum sulforaphane in exploratory analysis.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/sulforaphane-research/39929977.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92", "start_char": 0, "end_char": 1849, "text_sha256": "525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92"}
- experimental_model
- Randomized double-blind placebo-controlled trial with exploratory microbiome analysis
- exposure
- Daily broccoli sprout extract for 12 weeks
- limitations
- Primary target was 0.3 mmol/L; subgroup and microbiome results were exploratory and need confirmation.
- nutrient_topic
- Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. · Sulforaphane / SFN, stereochemistry specified per study
- organism
- Human prediabetes; 35 extract and 39 placebo participants analyzed
- plain_language
- Microbial conversion capacity may help explain exposure differences, but this was not a randomized microbial intervention.
- primary_references
- [sulforaphane-p39929977] Effect of broccoli sprout extract and baseline gut microbiota on fasting blood glucose in prediabetes: a randomized, placebo-controlled trial. (2025). https://pubmed.ncbi.nlm.nih.gov/39929977/ DOI: 10.1038/s41564-025-01932-w
- tissue_or_cell_type
- Fasting glucose and serum exposure
Sulforaphane: formation, electrophile sensing and nutrient connections (2026-09-17) · lines 1191–1202
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled trial with exploratory microbiome analysis · source_derived_draft · unverified_draft
### sulforaphane-microbiome-response Baseline abundance of the bacterial glucosinolate-conversion operon correlated with serum sulforaphane in exploratory analysis. Condition category: normal nutrient_topic: Sulforaphane research collection; topical membership is not evidence of a direct dietary effect. plain_language: Microbial conversion capacity may help explain exposure differences, but this was not a randomized microbial intervention. organism: Human prediabetes; 35 extract and 39 placebo participants analyzed tissue_or_cell_type: Fasting glucose and serum exposure experimental_model: Randomized double-blind placebo-controlled trial with exploratory microbiome analysis limitations: Primary target was 0.3 mmol/L; subgroup and microbiome results were exploratory and need confirmation. exposure: Daily broccoli sprout extract for 12 weeks evidence_span: {"source_cache": "artifacts/sulforaphane-research/39929977.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92", "start_char": 0, "end_char": 1849, "text_sha256": "525674c523bafc5e583bea8f2402f9e6dcf792c93b5af0c0f19d3aee15393a92"} [sulforaphane-p39929977] Effect of broccoli sprout extract and baseline gut microbiota on fasting blood glucose in prediabetes: a randomized, placebo-controlled trial. (2025). https://pubmed.ncbi.nlm.nih.gov/39929977/ DOI: 10.1038/s41564-025-01932-w
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.