Component
Glycocholate
Context-specific entity; species, compartment and exposure are stated on each claim.
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The same expressed human BAAT also catalyzed glycine conjugation of cholic acid.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Recombinant human enzyme.
- limitations
- Shared enzyme use does not establish clinical competition or a need to balance glycine and taurine supplements.
- nutrient_topic
- Taurine collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Taurine
- plain_language
- Glycine and taurine converge on the same bile-conjugating enzyme.
- primary_references
- Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. · 1994 · https://pubmed.ncbi.nlm.nih.gov/8034703/
Taurine: synthesis, transport, mitochondrial decoding and nutrient interactions (2026-09-19) · lines 305–311
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Recombinant human enzyme. · source_derived_draft · unverified_draft
## taurine-baat-glycine Glycine and taurine converge on the same bile-conjugating enzyme. The same expressed human BAAT also catalyzed glycine conjugation of cholic acid. Model: Recombinant human enzyme. Limitations: Shared enzyme use does not establish clinical competition or a need to balance glycine and taurine supplements. Evidence access: Primary abstract Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase. · 1994 · https://pubmed.ncbi.nlm.nih.gov/8034703/
Complete structured claim and evidence
Where it participates (unsigned role)
Adding taurocholic acid, but not glycocholic acid, to a low-fat mouse diet promoted Bilophila wadsworthia expansion.
Experimental context and source evidence
- evidence_access
- Primary abstract
- experimental_model
- Mouse dietary experiments with conjugate comparison.
- limitations
- The intervention was taurocholate, not free taurine alone; microbial community and host genotype matter.
- nutrient_topic
- Taurine collection; molecular form, preparation, species, exposure and manipulation remain explicit. · Taurine
- plain_language
- Taurine-conjugated bile supplies sulfur that certain microbes can exploit.
- primary_references
- Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. · 2012 · https://pubmed.ncbi.nlm.nih.gov/22722865/ · DOI 10.1038/nature11225
Taurine: synthesis, transport, mitochondrial decoding and nutrient interactions (2026-09-19) · lines 329–335
AI-assisted research curation; primary-abstract references and experimental limitations individually identified. Not publisher full text. · supports · Mouse dietary experiments with conjugate comparison. · source_derived_draft · unverified_draft
## taurine-microbial-bilophila Taurine-conjugated bile supplies sulfur that certain microbes can exploit. Adding taurocholic acid, but not glycocholic acid, to a low-fat mouse diet promoted Bilophila wadsworthia expansion. Model: Mouse dietary experiments with conjugate comparison. Limitations: The intervention was taurocholate, not free taurine alone; microbial community and host genotype matter. Evidence access: Primary abstract Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. · 2012 · https://pubmed.ncbi.nlm.nih.gov/22722865/ · DOI 10.1038/nature11225
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.