Component
Cinnamaldehyde bioaccessibility in simulated digestive fluids
Cinnamaldehyde bioaccessibility in simulated digestive fluids. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Cinnamaldehyde showed reported 100% bioaccessibility in the simulated fasted and fed gastric/intestinal fluids.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/ceylon-research/39845339.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "243c3bd561d9ff4d7dfe10fa748b1aacc0941a4ec9f712615f7dd7df4e98f118", "start_char": 0, "end_char": 1463, "text_sha256": "243c3bd561d9ff4d7dfe10fa748b1aacc0941a4ec9f712615f7dd7df4e98f118"}
- experimental_model
- Simulated digestion and human liver microsomal/S9 metabolism
- exposure
- Cinnamaldehyde alone or in the characterized C. verum oil
- limitations
- Bioaccessibility is not systemic bioavailability; the oxidation data do not assign a unique aldehyde-dehydrogenase isoform.
- nutrient_topic
- Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. · Ceylon cinnamon / Cinnamomum verum bark preparations
- organism
- Human-derived preparations and acellular digestive fluids
- plain_language
- It remained accessible in simulated digestion; this does not mean all of it reaches human blood unchanged.
- primary_references
- [ceylon-p39845339] Evaluation of bioaccessibility, metabolic clearance and interaction with xenobiotic receptors (PXR and AhR) of cinnamaldehyde. (2025). https://pubmed.ncbi.nlm.nih.gov/39845339/ DOI: 10.1016/j.fochms.2024.100237
- tissue_or_cell_type
- Gastric/intestinal simulations; liver fractions
Ceylon cinnamon: metabolism, signaling and nutrient connections (2026-09-17) · lines 259–270
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Simulated digestion and human liver microsomal/S9 metabolism · source_derived_draft · unverified_draft
### ceylon-bioaccessibility Cinnamaldehyde showed reported 100% bioaccessibility in the simulated fasted and fed gastric/intestinal fluids. Condition category: normal nutrient_topic: Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. plain_language: It remained accessible in simulated digestion; this does not mean all of it reaches human blood unchanged. organism: Human-derived preparations and acellular digestive fluids tissue_or_cell_type: Gastric/intestinal simulations; liver fractions experimental_model: Simulated digestion and human liver microsomal/S9 metabolism limitations: Bioaccessibility is not systemic bioavailability; the oxidation data do not assign a unique aldehyde-dehydrogenase isoform. exposure: Cinnamaldehyde alone or in the characterized C. verum oil evidence_span: {"source_cache": "artifacts/ceylon-research/39845339.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "243c3bd561d9ff4d7dfe10fa748b1aacc0941a4ec9f712615f7dd7df4e98f118", "start_char": 0, "end_char": 1463, "text_sha256": "243c3bd561d9ff4d7dfe10fa748b1aacc0941a4ec9f712615f7dd7df4e98f118"} [ceylon-p39845339] Evaluation of bioaccessibility, metabolic clearance and interaction with xenobiotic receptors (PXR and AhR) of cinnamaldehyde. (2025). https://pubmed.ncbi.nlm.nih.gov/39845339/ DOI: 10.1016/j.fochms.2024.100237
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.