Component
Child WPPSI-III verbal IQ score
Child WPPSI-III verbal IQ score. Study-specific scope and measurement methods are recorded with each claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Verbal IQ at 5–6 years averaged 89.5 versus 90.2 with maternal iodine versus placebo; reported difference −0.7 (95% CI −2.9 to 1.5), P=0.77.
Experimental context and source evidence
- availability_state
- nutrient_deficiency Imported condition classification; unverified.
- cross_nutrient
- false
- evidence_location
- Primary full PDF Methods; Table2 and Fig2; Discussion, pp.853–863.
- experimental_model
- Randomized double-blind placebo-controlled maternal trial in Bangkok and Bangalore; 832 women randomized, 313 children assessed for IQ and 315 for executive function at age 5–6
- exposure
- 200 micrograms iodine/day as potassium iodide until delivery; mean enrollment 10.7 weeks gestation; baseline median urinary iodine 131 micrograms/L; IQ iodine 159/placebo 154, executive function 159/156.
- limitations
- Mild group-level deficiency with site differences: Thailand deficient and India at low adequacy. Substantial attrition was balanced between groups; measured baseline characteristics were similar in those followed and lost. This does not test preconception treatment or severe deficiency. Reported differences, CIs and mixed-model P values are retained as published.
- nutrient_topic
- Iodine research collection; topical membership is not evidence of a direct dietary effect. · Iodine
- organism
- Homo sapiens
- plain_language
- Starting iodine during this mildly deficient pregnancy trial did not significantly improve verbal IQ.
- primary_references
- [iod-clin-gow2017] Effect of iodine supplementation in pregnant women on child neurodevelopment: a randomised, double-blind, placebo-controlled trial. (2017). https://pubmed.ncbi.nlm.nih.gov/29030199/ DOI: 10.1016/s2213-8587(17)30332-7
- tissue_or_cell_type
- Maternal iodine status and child neurodevelopment
- trigger_kind
- nutrient_deficiency Imported condition classification; unverified.
Iodine: thyroid hormone production, deficiency, excess and nutrient interactions (2026-09-17) · lines 1370–1382
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized double-blind placebo-controlled maternal trial in Bangkok and Bangalore; 832 women randomized, 313 children assessed for IQ and 315 for executive function at age 5–6 · source_derived_draft · unverified_draft
### iod-clin-pregnancy-verbal Verbal IQ at 5–6 years averaged 89.5 versus 90.2 with maternal iodine versus placebo; reported difference −0.7 (95% CI −2.9 to 1.5), P=0.77. Condition category: nutrient_deficiency nutrient_topic: Iodine research collection; topical membership is not evidence of a direct dietary effect. plain_language: Starting iodine during this mildly deficient pregnancy trial did not significantly improve verbal IQ. organism: Homo sapiens tissue_or_cell_type: Maternal iodine status and child neurodevelopment experimental_model: Randomized double-blind placebo-controlled maternal trial in Bangkok and Bangalore; 832 women randomized, 313 children assessed for IQ and 315 for executive function at age 5–6 limitations: Mild group-level deficiency with site differences: Thailand deficient and India at low adequacy. Substantial attrition was balanced between groups; measured baseline characteristics were similar in those followed and lost. This does not test preconception treatment or severe deficiency. Reported differences, CIs and mixed-model P values are retained as published. exposure: 200 micrograms iodine/day as potassium iodide until delivery; mean enrollment 10.7 weeks gestation; baseline median urinary iodine 131 micrograms/L; IQ iodine 159/placebo 154, executive function 159/156. cross_nutrient: false evidence_location: Primary full PDF Methods; Table2 and Fig2; Discussion, pp.853–863. [iod-clin-gow2017] Effect of iodine supplementation in pregnant women on child neurodevelopment: a randomised, double-blind, placebo-controlled trial. (2017). https://pubmed.ncbi.nlm.nih.gov/29030199/ DOI: 10.1016/s2213-8587(17)30332-7
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.