Component
Cellular boric-acid-equivalent transport
Cellular boric-acid-equivalent transport. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Pufferfish Slc4a11A expression increased boron accumulation, intracellular pH and outward currents during boric-acid exposure in oocytes, independently of extracellular sodium.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/boron-research/36435196.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f33e845c95cab0ebe899c99562ebb23f43292cbab645601a5ab51a421fdc5f8c", "start_char": 0, "end_char": 1651, "text_sha256": "f33e845c95cab0ebe899c99562ebb23f43292cbab645601a5ab51a421fdc5f8c"}
- experimental_model
- Freshwater/seawater acclimation and Xenopus oocyte transporter expression
- exposure
- Freshwater versus seawater; boric-acid exposure during voltage clamp
- limitations
- Fish paralog is distinct from human SLC4A11. Borate uniport, boric-acid/OH cotransport and boric-acid/H exchange were not distinguished.
- nutrient_topic
- Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
- organism
- Takifugu obscurus pufferfish; Xenopus expression host
- plain_language
- A fish version really did transport boric-acid equivalents in this experiment; that does not validate the disputed human assignment.
- primary_references
- [boron-p36435196] Seawater fish use an electrogenic boric acid transporter, Slc4a11A, for boric acid excretion by the kidney. (2023). https://pubmed.ncbi.nlm.nih.gov/36435196/ DOI: 10.1016/j.jbc.2022.102740
- tissue_or_cell_type
- Kidney tubular apical membrane and heterologous membrane
Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 248–259
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Freshwater/seawater acclimation and Xenopus oocyte transporter expression · source_derived_draft · unverified_draft
### boron-pufferfish-transporter Pufferfish Slc4a11A expression increased boron accumulation, intracellular pH and outward currents during boric-acid exposure in oocytes, independently of extracellular sodium. Condition category: normal nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: A fish version really did transport boric-acid equivalents in this experiment; that does not validate the disputed human assignment. organism: Takifugu obscurus pufferfish; Xenopus expression host tissue_or_cell_type: Kidney tubular apical membrane and heterologous membrane experimental_model: Freshwater/seawater acclimation and Xenopus oocyte transporter expression limitations: Fish paralog is distinct from human SLC4A11. Borate uniport, boric-acid/OH cotransport and boric-acid/H exchange were not distinguished. exposure: Freshwater versus seawater; boric-acid exposure during voltage clamp evidence_span: {"source_cache": "artifacts/boron-research/36435196.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "f33e845c95cab0ebe899c99562ebb23f43292cbab645601a5ab51a421fdc5f8c", "start_char": 0, "end_char": 1651, "text_sha256": "f33e845c95cab0ebe899c99562ebb23f43292cbab645601a5ab51a421fdc5f8c"} [boron-p36435196] Seawater fish use an electrogenic boric acid transporter, Slc4a11A, for boric acid excretion by the kidney. (2023). https://pubmed.ncbi.nlm.nih.gov/36435196/ DOI: 10.1016/j.jbc.2022.102740
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.