Component
Cardiolipin enrichment and clustering in a membrane
Cardiolipin enrichment and clustering in a membrane. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Mitochondrial creatine kinase selectively recruited cardiolipin and promoted lipid clustering in the tested reconstituted membranes.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/creatine-research/19289067.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3880cefa5c138a1e112b50ad2d734e8f38c70da3a545aff80969e7aa1e9a5666", "start_char": 0, "end_char": 1484, "text_sha256": "3880cefa5c138a1e112b50ad2d734e8f38c70da3a545aff80969e7aa1e9a5666"}
- experimental_model
- Protein–lipid monolayer and mixed-membrane experiments
- exposure
- Creatine kinase added to cardiolipin or mixed phospholipid films
- limitations
- Mitochondrial CK family record; the specific human isoform is not assigned from this abstract. Reconstituted membrane experiment; no human outcome.
- nutrient_topic
- Creatine research collection; topical membership is not evidence of a direct dietary effect. · Creatine
- organism
- Mitochondrial creatine kinase in reconstituted lipid systems
- plain_language
- The enzyme can help organize the membrane lipids around it.
- primary_references
- [creatine-p19289067] Mitochondrial creatine kinase binding to phospholipid monolayers induces cardiolipin segregation. (2009). https://pubmed.ncbi.nlm.nih.gov/19289067/ DOI: 10.1016/j.bpj.2008.12.3911
- tissue_or_cell_type
- Synthetic cardiolipin-containing membranes
Creatine: synthesis, transport, phosphocreatine energetics and nutrient interactions (2026-09-17) · lines 373–384
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Protein–lipid monolayer and mixed-membrane experiments · source_derived_draft · unverified_draft
### creatine-mtck-cardiolipin Mitochondrial creatine kinase selectively recruited cardiolipin and promoted lipid clustering in the tested reconstituted membranes. Condition category: normal nutrient_topic: Creatine research collection; topical membership is not evidence of a direct dietary effect. plain_language: The enzyme can help organize the membrane lipids around it. organism: Mitochondrial creatine kinase in reconstituted lipid systems tissue_or_cell_type: Synthetic cardiolipin-containing membranes experimental_model: Protein–lipid monolayer and mixed-membrane experiments limitations: Mitochondrial CK family record; the specific human isoform is not assigned from this abstract. Reconstituted membrane experiment; no human outcome. exposure: Creatine kinase added to cardiolipin or mixed phospholipid films evidence_span: {"source_cache": "artifacts/creatine-research/19289067.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3880cefa5c138a1e112b50ad2d734e8f38c70da3a545aff80969e7aa1e9a5666", "start_char": 0, "end_char": 1484, "text_sha256": "3880cefa5c138a1e112b50ad2d734e8f38c70da3a545aff80969e7aa1e9a5666"} [creatine-p19289067] Mitochondrial creatine kinase binding to phospholipid monolayers induces cardiolipin segregation. (2009). https://pubmed.ncbi.nlm.nih.gov/19289067/ DOI: 10.1016/j.bpj.2008.12.3911
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.