Component
Caffeic acid disappearance before ileostomy collection
Caffeic acid disappearance before ileostomy collection. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
Caffeic-acid disappearance was 95 +/- 4% in the same crossover design.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/chlorogenic_acid-research/11208940.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "651ac6849ea1490afeee5c905352bda75c8701decbcdf68f1d22dec05af06fd8", "start_char": 0, "end_char": 1299, "text_sha256": "651ac6849ea1490afeee5c905352bda75c8701decbcdf68f1d22dec05af06fd8"}
- experimental_model
- Randomized-order crossover in seven ileostomy volunteers
- exposure
- 2.8 mmol chlorogenic acid or caffeic acid on separate days; 24-hour collections
- limitations
- Disappearance from ileal effluent is not intact-parent systemic bioavailability. Participants lacked normal colonic processing; no therapeutic outcome was tested.
- nutrient_topic
- Chlorogenic acid research collection; topical membership is not evidence of a direct dietary effect. · Chlorogenic acid / 5-O-caffeoylquinic acid
- organism
- Human
- plain_language
- The free acid behaved differently from its quinic-acid ester.
- primary_references
- [chlorogenic_acid-p11208940] Chlorogenic acid and caffeic acid are absorbed in humans. (2001). https://pubmed.ncbi.nlm.nih.gov/11208940/ DOI: 10.1093/jn/131.1.66
- tissue_or_cell_type
- Small intestine; ileal effluent and urine
Chlorogenic acid: metabolism, signaling and nutrient connections (2026-09-17) · lines 152–163
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized-order crossover in seven ileostomy volunteers · source_derived_draft · unverified_draft
### chlorogenic_acid-caffeic-disappearance Caffeic-acid disappearance was 95 +/- 4% in the same crossover design. Condition category: normal nutrient_topic: Chlorogenic acid research collection; topical membership is not evidence of a direct dietary effect. plain_language: The free acid behaved differently from its quinic-acid ester. organism: Human tissue_or_cell_type: Small intestine; ileal effluent and urine experimental_model: Randomized-order crossover in seven ileostomy volunteers limitations: Disappearance from ileal effluent is not intact-parent systemic bioavailability. Participants lacked normal colonic processing; no therapeutic outcome was tested. exposure: 2.8 mmol chlorogenic acid or caffeic acid on separate days; 24-hour collections evidence_span: {"source_cache": "artifacts/chlorogenic_acid-research/11208940.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "651ac6849ea1490afeee5c905352bda75c8701decbcdf68f1d22dec05af06fd8", "start_char": 0, "end_char": 1299, "text_sha256": "651ac6849ea1490afeee5c905352bda75c8701decbcdf68f1d22dec05af06fd8"} [chlorogenic_acid-p11208940] Chlorogenic acid and caffeic acid are absorbed in humans. (2001). https://pubmed.ncbi.nlm.nih.gov/11208940/ DOI: 10.1093/jn/131.1.66
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.