Component

Bone magnesium concentration

Bone magnesium concentration. Species, exposure and limitations are retained in each linked claim.

1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. Boron-deprived rats with marginal methionine had lower bone magnesium; interactions with magnesium deprivation were strongest under severe restriction and abundant arginine.

    Boron → Bone magnesium concentration source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    nutrient_deficiency Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/boron-research/2484371.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "324fa75871a385d9890c32c6d4ddd62af6fff561174e439afb94f3bd4662ed13", "start_char": 0, "end_char": 2179, "text_sha256": "324fa75871a385d9890c32c6d4ddd62af6fff561174e439afb94f3bd4662ed13"}
    experimental_model
    Nine factorial dietary experiments in rats
    exposure
    Six to ten weeks; boron supplement 0 or 3 µg/g; magnesium 100/200 versus 400 µg/g; methionine and arginine contexts varied
    limitations
    Dependence on severe magnesium restriction and amino-acid background is central. Rat growth/bone findings do not establish an essential human role, a methylation mechanism or a human rescue regimen.
    nutrient_topic
    Boron research collection; topical membership is not evidence of a direct dietary effect. · Boron
    organism
    Sprague-Dawley rats and one spontaneously hypertensive rat experiment
    plain_language
    The effect of low boron depended strongly on the rest of the diet.
    primary_references
    [boron-p2484371] Magnesium and methionine deprivation affect the response of rats to boron deprivation. (1988). https://pubmed.ncbi.nlm.nih.gov/2484371/ DOI: 10.1007/bf02795449
    tissue_or_cell_type
    Whole-animal growth and bone mineral endpoints
    trigger_kind
    nutrient_deficiency Imported condition classification; unverified.

    Boron: chemistry, nutrient interactions, low-intake studies and mechanistic uncertainties (2026-09-17) · lines 794–805

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Nine factorial dietary experiments in rats · source_derived_draft · unverified_draft

    ### boron-rat-mg-amino-acid-context Boron-deprived rats with marginal methionine had lower bone magnesium; interactions with magnesium deprivation were strongest under severe restriction and abundant arginine. Condition category: nutrient_deficiency nutrient_topic: Boron research collection; topical membership is not evidence of a direct dietary effect. plain_language: The effect of low boron depended strongly on the rest of the diet. organism: Sprague-Dawley rats and one spontaneously hypertensive rat experiment tissue_or_cell_type: Whole-animal growth and bone mineral endpoints experimental_model: Nine factorial dietary experiments in rats limitations: Dependence on severe magnesium restriction and amino-acid background is central. Rat growth/bone findings do not establish an essential human role, a methylation mechanism or a human rescue regimen. exposure: Six to ten weeks; boron supplement 0 or 3 µg/g; magnesium 100/200 versus 400 µg/g; methionine and arginine contexts varied evidence_span: {"source_cache": "artifacts/boron-research/2484371.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "324fa75871a385d9890c32c6d4ddd62af6fff561174e439afb94f3bd4662ed13", "start_char": 0, "end_char": 2179, "text_sha256": "324fa75871a385d9890c32c6d4ddd62af6fff561174e439afb94f3bd4662ed13"} [boron-p2484371] Magnesium and methionine deprivation affect the response of rats to boron deprivation. (1988). https://pubmed.ncbi.nlm.nih.gov/2484371/ DOI: 10.1007/bf02795449
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards