Component
Bilitranslocase carrier activity in the 2002 assay; gene assignment unresolved
Bilitranslocase carrier activity in the 2002 assay; gene assignment unresolved. Interpret through the linked experimental species, preparation, compartment and exposure; no universal causal effect is implied.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The tested anthocyanin structures competed in a bilitranslocase transport assay; the class result was 17 of 20 compounds, Ki 1.4-22 uM.
Experimental context and source evidence
- evidence_access
- Primary indexed abstract reviewed; full methods, figures, exact doses or endpoint-specific species assignments may remain unextracted.
- experimental_contrast
- {"intervention": "Test anthocyanin addition", "comparator": "Carrier assay without added anthocyanin", "endpoint": "The tested anthocyanin structures competed in a bilitranslocase transport assay; the class result was 17 of 20 compounds, Ki 1.4-22 uM.", "effect_direction": "decrease", "combination": "single", "conditions": []} Explicit extracted experimental comparison; source-derived draft.
- experimental_model
- Cell-free membrane-carrier transport inhibition assay; individual constants not extracted.
- interpretation_status
- Source-derived extraction of a fact-checked reference; access is explicit, not independent raw-data verification.
- limitations
- Competition supports interaction, not a complete human absorption mechanism or an inferred transporter-gene identity.
- plain_language
- The tested anthocyanin structures competed in a bilitranslocase transport assay; the class result was 17 of 20 compounds, Ki 1.4-22 uM.
- primary_references
- The interaction of anthocyanins with bilitranslocase. | 2002 | DOI 10.1016/s0006-291x(02)00927-0 | PMID 12176028 | https://pubmed.ncbi.nlm.nih.gov/12176028/ | https://doi.org/10.1016/s0006-291x(02)00927-0 | https://doi.org/10.1016/S0006-291X%2802%2900927-0
- source_locator
- Reviewed reference lines 42-42; exact primary location described in quoted passage where extracted.
Anthocyanins: detailed mechanisms of action (reviewed 4 October 2026) · lines 42–42
Original AI-assisted review of primary studies and, where relevant, official regulatory records. Access level is retained per claim. Corrections, null results and unresolved questions remain explicit. Not publisher full text or independent replication. · supports · Cell-free membrane-carrier transport inhibition assay; individual constants not extracted. · source_derived_draft · unverified_draft
**Bilitranslocase remains a candidate route.** Seventeen of twenty tested anthocyanin-related compounds competitively inhibited a bilitranslocase transport assay, with reported inhibition constants of 1.4–22 µM. Glycosylated compounds often interacted more strongly than their aglycones. Competition in a carrier assay is useful evidence, but does not determine how much pigment crosses the human stomach. The assay-associated carrier should not be silently assigned an unrelated established transporter gene. [Passamonti et al., 2002](https://doi.org/10.1016/S0006-291X%2802%2900927-0).
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.