Component

Bacteroides sp. MANG inducible C-glucosyl-cleaving activity, molecular identity unresolved

Bacteroides sp. MANG inducible C-glucosyl-cleaving activity, molecular identity unresolved. Species, exposure and limitations are retained in each linked claim.

3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What it acts on

  1. An inducible activity in Bacteroides sp. MANG cleaved mangiferin to norathyriol.

    Bacteroides sp. MANG inducible C-glucosyl-cleaving activity, molecular identity unresolved → Norathyriol source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"}
    experimental_model
    Isolated anaerobic human-fecal bacterium and cell-free extracts
    exposure
    Mangiferin culture exposure, with transcription/translation inhibitors
    limitations
    One isolate; activity identity unresolved; not a prediction of every human microbiome.
    nutrient_topic
    Mangiferin research collection; topical membership is not evidence of a direct dietary effect. · Mangiferin
    organism
    Bacteroides sp. MANG
    plain_language
    A bacterial system removes the attached sugar.
    primary_references
    [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    tissue_or_cell_type
    Bacterial culture

    Mangiferin: metabolism, signaling and nutrient connections (2026-09-17) · lines 106–117

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Isolated anaerobic human-fecal bacterium and cell-free extracts · source_derived_draft · unverified_draft

    ### mangiferin-bacterial-cleavage An inducible activity in Bacteroides sp. MANG cleaved mangiferin to norathyriol. Condition category: normal nutrient_topic: Mangiferin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A bacterial system removes the attached sugar. organism: Bacteroides sp. MANG tissue_or_cell_type: Bacterial culture experimental_model: Isolated anaerobic human-fecal bacterium and cell-free extracts limitations: One isolate; activity identity unresolved; not a prediction of every human microbiome. exposure: Mangiferin culture exposure, with transcription/translation inhibitors evidence_span: {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"} [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    Complete structured claim and evidence

What acts on it

  1. The chloramphenicol treatment abolished the induced C-glucosyl-cleaving activity.

    Chloramphenicol → Bacteroides sp. MANG inducible C-glucosyl-cleaving activity, molecular identity unresolved source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    machinery_impairment Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"}
    experimental_model
    Isolated anaerobic human-fecal bacterium and cell-free extracts
    exposure
    Mangiferin culture exposure, with transcription/translation inhibitors
    limitations
    One isolate; activity identity unresolved; not a prediction of every human microbiome.
    nutrient_topic
    Mangiferin research collection; topical membership is not evidence of a direct dietary effect. · Mangiferin
    organism
    Bacteroides sp. MANG
    plain_language
    Conversion requires functioning bacterial gene-expression machinery.
    primary_references
    [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    tissue_or_cell_type
    Bacterial culture
    trigger_kind
    machinery_impairment Imported condition classification; unverified.

    Mangiferin: metabolism, signaling and nutrient connections (2026-09-17) · lines 132–143

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Isolated anaerobic human-fecal bacterium and cell-free extracts · source_derived_draft · unverified_draft

    ### mangiferin-chloramphenicol-cleavage The chloramphenicol treatment abolished the induced C-glucosyl-cleaving activity. Condition category: machinery_impairment nutrient_topic: Mangiferin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Conversion requires functioning bacterial gene-expression machinery. organism: Bacteroides sp. MANG tissue_or_cell_type: Bacterial culture experimental_model: Isolated anaerobic human-fecal bacterium and cell-free extracts limitations: One isolate; activity identity unresolved; not a prediction of every human microbiome. exposure: Mangiferin culture exposure, with transcription/translation inhibitors evidence_span: {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"} [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    Complete structured claim and evidence

  2. The rifampicin treatment abolished the induced C-glucosyl-cleaving activity.

    Rifampicin → Bacteroides sp. MANG inducible C-glucosyl-cleaving activity, molecular identity unresolved source_derived_draftungraded
    Experimental context and source evidence
    availability_state
    machinery_impairment Imported condition classification; unverified.
    evidence_span
    {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"}
    experimental_model
    Isolated anaerobic human-fecal bacterium and cell-free extracts
    exposure
    Mangiferin culture exposure, with transcription/translation inhibitors
    limitations
    One isolate; activity identity unresolved; not a prediction of every human microbiome.
    nutrient_topic
    Mangiferin research collection; topical membership is not evidence of a direct dietary effect. · Mangiferin
    organism
    Bacteroides sp. MANG
    plain_language
    Conversion requires functioning bacterial gene-expression machinery.
    primary_references
    [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    tissue_or_cell_type
    Bacterial culture
    trigger_kind
    machinery_impairment Imported condition classification; unverified.

    Mangiferin: metabolism, signaling and nutrient connections (2026-09-17) · lines 119–130

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Isolated anaerobic human-fecal bacterium and cell-free extracts · source_derived_draft · unverified_draft

    ### mangiferin-rifampicin-cleavage The rifampicin treatment abolished the induced C-glucosyl-cleaving activity. Condition category: machinery_impairment nutrient_topic: Mangiferin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Conversion requires functioning bacterial gene-expression machinery. organism: Bacteroides sp. MANG tissue_or_cell_type: Bacterial culture experimental_model: Isolated anaerobic human-fecal bacterium and cell-free extracts limitations: One isolate; activity identity unresolved; not a prediction of every human microbiome. exposure: Mangiferin culture exposure, with transcription/translation inhibitors evidence_span: {"source_cache": "artifacts/mangiferin-research/16141538.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88", "start_char": 0, "end_char": 1356, "text_sha256": "9bf5373ce89587337b6d0520b931f202d44771dba205220b8e340b9fa7446b88"} [mangiferin-p16141538] Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond. (2005). https://pubmed.ncbi.nlm.nih.gov/16141538/ DOI: 10.1248/bpb.28.1672
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards