Component
Apple cider vinegar as used in the type 1 diabetes trial
Apple cider vinegar as used in the type 1 diabetes trial. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
In patients with type 1 diabetes and diabetic gastroparesis the median gastric emptying rate was 27% without vinegar and 17% with vinegar, a statistically significant reduction, and the authors concluded this might be a disadvantage for their glycaemic control.
Experimental context and source evidence
- availability_state
- biomarker_context Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/acetate-research/18093343.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "092c8db0cd31e510e21838bd5ad6cc16876368af06584a2fc6d44efa2e189439", "start_char": 0, "end_char": 1477, "text_sha256": "092c8db0cd31e510e21838bd5ad6cc16876368af06584a2fc6d44efa2e189439"}
- experimental_model
- Investigator-blinded crossover in ten patients with type 1 diabetes and diabetic gastroparesis
- exposure
- 30 ml apple cider vinegar in 200 ml water daily before breakfast for two weeks, with gastric emptying measured by standardised real-time ultrasonography after 300 g rice pudding
- limitations
- Ten patients, one of whom had undergone vagotomy. It is recorded because the same mechanism that is read as a benefit in healthy people is unwanted in people whose stomachs already empty too slowly.
- nutrient_topic
- Acetic acid research collection; topical membership is not evidence of a direct clinical effect, and the ingested acid is recorded separately from the circulating acetate anion. · Acetic acid
- organism
- Human
- plain_language
- In people whose stomachs already empty too slowly, vinegar made that worse.
- primary_references
- [acetate-p18093343] Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. (2007). https://pubmed.ncbi.nlm.nih.gov/18093343/ DOI: 10.1186/1471-230x-7-46
- tissue_or_cell_type
- Stomach
- trigger_kind
- biomarker_context Imported condition classification; unverified.
Acetic acid: the ingested acid, the receptors acetate binds, the acetyl-CoA it becomes, and the acetyl groups that reach histones (2026-09-21) · lines 186–197
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Investigator-blinded crossover in ten patients with type 1 diabetes and diabetic gastroparesis · source_derived_draft · unverified_draft
### acetate-vinegar-worsens-gastroparesis In patients with type 1 diabetes and diabetic gastroparesis the median gastric emptying rate was 27% without vinegar and 17% with vinegar, a statistically significant reduction, and the authors concluded this might be a disadvantage for their glycaemic control. Condition category: biomarker_context nutrient_topic: Acetic acid research collection; topical membership is not evidence of a direct clinical effect, and the ingested acid is recorded separately from the circulating acetate anion. plain_language: In people whose stomachs already empty too slowly, vinegar made that worse. organism: Human tissue_or_cell_type: Stomach experimental_model: Investigator-blinded crossover in ten patients with type 1 diabetes and diabetic gastroparesis limitations: Ten patients, one of whom had undergone vagotomy. It is recorded because the same mechanism that is read as a benefit in healthy people is unwanted in people whose stomachs already empty too slowly. exposure: 30 ml apple cider vinegar in 200 ml water daily before breakfast for two weeks, with gastric emptying measured by standardised real-time ultrasonography after 300 g rice pudding evidence_span: {"source_cache": "artifacts/acetate-research/18093343.abstract.txt", "locator": "Indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "092c8db0cd31e510e21838bd5ad6cc16876368af06584a2fc6d44efa2e189439", "start_char": 0, "end_char": 1477, "text_sha256": "092c8db0cd31e510e21838bd5ad6cc16876368af06584a2fc6d44efa2e189439"} [acetate-p18093343] Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. (2007). https://pubmed.ncbi.nlm.nih.gov/18093343/ DOI: 10.1186/1471-230x-7-46
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.