Component
Clinician-rated tic severity
Clinician-rated tic severity. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The mixture group improved clinician-rated tics more than psychoeducation in the open-label trial.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/theanine-research/35215501.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "68809f3eaf29616aa35c472872e3c510e0c8aaf23e8880c43a91f363eaad5ea2", "start_char": 0, "end_char": 1576, "text_sha256": "68809f3eaf29616aa35c472872e3c510e0c8aaf23e8880c43a91f363eaad5ea2"}
- experimental_model
- Randomized open-label comparative trial
- exposure
- Theanine plus vitamin B6 versus psychoeducation
- limitations
- No blinded placebo and no single-ingredient arms. Cannot attribute the effect to either ingredient or prove biochemical synergy.
- nutrient_topic
- L-Theanine research collection; topical membership is not evidence of a direct dietary effect. · L-Theanine
- organism
- 34 children with Tourette syndrome or chronic tic disorder and anxiety
- plain_language
- This preliminary combination result does not show that B6 makes theanine work in everyone.
- primary_references
- [theanine-p35215501] Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study. (2022). https://pubmed.ncbi.nlm.nih.gov/35215501/ DOI: 10.3390/nu14040852
- tissue_or_cell_type
- Clinician-rated tics and anxiety
L-Theanine: metabolism, neural signaling, nutrient connections and human outcomes (2026-09-17) · lines 874–885
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Randomized open-label comparative trial · source_derived_draft · unverified_draft
### theanine-b6-mixture-tics The mixture group improved clinician-rated tics more than psychoeducation in the open-label trial. Condition category: normal nutrient_topic: L-Theanine research collection; topical membership is not evidence of a direct dietary effect. plain_language: This preliminary combination result does not show that B6 makes theanine work in everyone. organism: 34 children with Tourette syndrome or chronic tic disorder and anxiety tissue_or_cell_type: Clinician-rated tics and anxiety experimental_model: Randomized open-label comparative trial limitations: No blinded placebo and no single-ingredient arms. Cannot attribute the effect to either ingredient or prove biochemical synergy. exposure: Theanine plus vitamin B6 versus psychoeducation evidence_span: {"source_cache": "artifacts/theanine-research/35215501.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "68809f3eaf29616aa35c472872e3c510e0c8aaf23e8880c43a91f363eaad5ea2", "start_char": 0, "end_char": 1576, "text_sha256": "68809f3eaf29616aa35c472872e3c510e0c8aaf23e8880c43a91f363eaad5ea2"} [theanine-p35215501] Use of Nutritional Supplements Based on L-Theanine and Vitamin B6 in Children with Tourette Syndrome, with Anxiety Disorders: A Pilot Study. (2022). https://pubmed.ncbi.nlm.nih.gov/35215501/ DOI: 10.3390/nu14040852
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.