Component
Thyrocyte basolateral membrane
Thyroid follicular-cell membrane facing interstitial/blood side.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The 2026 Finnish SLC26A7 study reported basolateral SLC26A7 localization in human thyrocytes, with intense staining in hyperthyroid samples.
Experimental context and source evidence
- cross_nutrient
- false
- experimental_model
- Six human thyroid samples including two homozygous carriers, goitrous/hyperactive samples and controls; additional mouse models
- exposure
- Six human tissue samples spanning carriers, goitrous/hyperactive tissues and controls; abstract-level tissue localization result.
- limitations
- Small heterogeneous tissue set and abstract-only extraction; this differs from the 2019 apical result and does not prove all thyroid contexts share one location.
- nutrient_topic
- Iodine research collection; topical membership is not evidence of a direct dietary effect. · Iodine
- organism
- Homo sapiens
- plain_language
- A later human thyroid study placed SLC26A7 on the blood-facing side.
- primary_references
- [iodine-trans-slc26a7-localization2026] Finnish-Enriched SLC26A7 Variant in Congenital Hypothyroidism: Clinical Spectrum, Thyroid Histopathology, and Expression Analysis. (2026). https://pubmed.ncbi.nlm.nih.gov/41791885/ DOI: 10.1177/10507256251411983
- tissue_or_cell_type
- Human thyroid tissue
Iodine: thyroid hormone production, deficiency, excess and nutrient interactions (2026-09-17) · lines 479–490
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Six human thyroid samples including two homozygous carriers, goitrous/hyperactive samples and controls; additional mouse models · source_derived_draft · unverified_draft
### iodine-trans-a7-basolateral2026 The 2026 Finnish SLC26A7 study reported basolateral SLC26A7 localization in human thyrocytes, with intense staining in hyperthyroid samples. Condition category: normal nutrient_topic: Iodine research collection; topical membership is not evidence of a direct dietary effect. plain_language: A later human thyroid study placed SLC26A7 on the blood-facing side. organism: Homo sapiens tissue_or_cell_type: Human thyroid tissue experimental_model: Six human thyroid samples including two homozygous carriers, goitrous/hyperactive samples and controls; additional mouse models limitations: Small heterogeneous tissue set and abstract-only extraction; this differs from the 2019 apical result and does not prove all thyroid contexts share one location. exposure: Six human tissue samples spanning carriers, goitrous/hyperactive tissues and controls; abstract-level tissue localization result. cross_nutrient: false [iodine-trans-slc26a7-localization2026] Finnish-Enriched SLC26A7 Variant in Congenital Hypothyroidism: Clinical Spectrum, Thyroid Histopathology, and Expression Analysis. (2026). https://pubmed.ncbi.nlm.nih.gov/41791885/ DOI: 10.1177/10507256251411983
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.