Component
Sweat-duct sodium chloride reabsorption
Sweat-duct sodium chloride reabsorption. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
CF sweat ducts showed low chloride permeability and impaired NaCl reabsorption.
Experimental context and source evidence
- availability_state
- machinery_impairment Imported condition classification; unverified.
- evidence_span
- {"source_cache": "artifacts/chloride-research/6823316.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8ce2ab2d15d30590a4e4d13e12060fc8656238cea8856a2aad03ed9e2e4dcee4", "start_char": 0, "end_char": 642, "text_sha256": "8ce2ab2d15d30590a4e4d13e12060fc8656238cea8856a2aad03ed9e2e4dcee4"}
- experimental_model
- Microperfusion of isolated sweat ducts
- exposure
- Cystic fibrosis versus control
- limitations
- Predates molecular CFTR identification; does not equate sweat chloride with blood chloride.
- nutrient_topic
- Chloride research collection; topical membership is not evidence of a direct dietary effect. · Chloride
- organism
- Human controls and cystic fibrosis patients
- plain_language
- A salty sweat measurement can reflect failure to reclaim salt, not excessive intake.
- primary_references
- [chloride-p6823316] Chloride impermeability in cystic fibrosis. (1983). https://pubmed.ncbi.nlm.nih.gov/6823316/ DOI: 10.1038/301421a0
- tissue_or_cell_type
- Sweat duct
- trigger_kind
- machinery_impairment Imported condition classification; unverified.
Chloride: transport, acid-base balance, nutrient interactions and loss states (2026-09-17) · lines 874–885
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Microperfusion of isolated sweat ducts · source_derived_draft · unverified_draft
### chloride-sweat-reabsorption CF sweat ducts showed low chloride permeability and impaired NaCl reabsorption. Condition category: machinery_impairment nutrient_topic: Chloride research collection; topical membership is not evidence of a direct dietary effect. plain_language: A salty sweat measurement can reflect failure to reclaim salt, not excessive intake. organism: Human controls and cystic fibrosis patients tissue_or_cell_type: Sweat duct experimental_model: Microperfusion of isolated sweat ducts limitations: Predates molecular CFTR identification; does not equate sweat chloride with blood chloride. exposure: Cystic fibrosis versus control evidence_span: {"source_cache": "artifacts/chloride-research/6823316.abstract.txt", "locator": "Exact primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "8ce2ab2d15d30590a4e4d13e12060fc8656238cea8856a2aad03ed9e2e4dcee4", "start_char": 0, "end_char": 642, "text_sha256": "8ce2ab2d15d30590a4e4d13e12060fc8656238cea8856a2aad03ed9e2e4dcee4"} [chloride-p6823316] Chloride impermeability in cystic fibrosis. (1983). https://pubmed.ncbi.nlm.nih.gov/6823316/ DOI: 10.1038/301421a0
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.