Component
Human StARD3 / MLN64 lutein-binding protein
Human StARD3 / MLN64 lutein-binding protein. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Recombinant human StARD3 bound lutein selectively, with dissociation constant 0.45 micromolar.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/lutein-research/21322544.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "e0362dd86389ecba7d75e2628ffcd785ea404e40a709084dd5a0749a4cfb89fa", "start_char": 0, "end_char": 1825, "text_sha256": "e0362dd86389ecba7d75e2628ffcd785ea404e40a709084dd5a0749a4cfb89fa"}
- experimental_model
- Recombinant binding assays and primate retinal localization
- exposure
- Surface plasmon resonance and immunohistochemistry
- limitations
- Binding does not prove net retinal delivery or clinical benefit; localization is from monkey tissue.
- nutrient_topic
- Lutein research collection; topical membership is not evidence of a direct dietary effect. · Lutein
- organism
- Human protein and monkey retinal tissue
- plain_language
- A retinal protein selectively holds lutein.
- primary_references
- [lutein-p21322544] Identification of StARD3 as a lutein-binding protein in the macula of the primate retina. (2011). https://pubmed.ncbi.nlm.nih.gov/21322544/ DOI: 10.1021/bi101906y
- tissue_or_cell_type
- Retina and purified protein
Lutein: metabolism, signaling and nutrient connections (2026-09-17) · lines 125–136
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Recombinant binding assays and primate retinal localization · source_derived_draft · unverified_draft
### lutein-stard3-binding Recombinant human StARD3 bound lutein selectively, with dissociation constant 0.45 micromolar. Condition category: normal nutrient_topic: Lutein research collection; topical membership is not evidence of a direct dietary effect. plain_language: A retinal protein selectively holds lutein. organism: Human protein and monkey retinal tissue tissue_or_cell_type: Retina and purified protein experimental_model: Recombinant binding assays and primate retinal localization limitations: Binding does not prove net retinal delivery or clinical benefit; localization is from monkey tissue. exposure: Surface plasmon resonance and immunohistochemistry evidence_span: {"source_cache": "artifacts/lutein-research/21322544.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "e0362dd86389ecba7d75e2628ffcd785ea404e40a709084dd5a0749a4cfb89fa", "start_char": 0, "end_char": 1825, "text_sha256": "e0362dd86389ecba7d75e2628ffcd785ea404e40a709084dd5a0749a4cfb89fa"} [lutein-p21322544] Identification of StARD3 as a lutein-binding protein in the macula of the primate retina. (2011). https://pubmed.ncbi.nlm.nih.gov/21322544/ DOI: 10.1021/bi101906y
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.