Component
SLC25A29
Independent protein record; interpretation is limited by each linked claim and its study context.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
Reconstituted human SLC25A29 transports lysine by uniport and exchange, supporting lysine entry into the mitochondrial matrix.
Experimental context and source evidence
- experimental_model
- Purified recombinant carrier reconstituted in liposomes
- limitations
- Physiological import role is inferred from transport properties and localization; not a carnitine transporter.
- organism
- Homo sapiens
- plain_language
- SLC25A29 gives lysine access to mitochondrial metabolism.
- primary_references
- [porcelli2014] The Human Gene SLC25A29, of Solute Carrier Family 25, Encodes a Mitochondrial Transporter of Basic Amino Acids (2014). https://pmc.ncbi.nlm.nih.gov/articles/PMC4036346/ DOI: 10.1074/jbc.M114.547448
- tissue_or_cell_type
- Inner mitochondrial membrane
- transport_effect
- raises Uniport and exchange supporting lysine entry into the matrix.
- transport_pool
- the mitochondrial matrix Uniport and exchange supporting lysine entry into the matrix.
L-Lysine: mechanism-first literature curation (2026-09-17) · lines 44–52
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified recombinant carrier reconstituted in liposomes · source_derived_draft · unverified_draft
### mitochondrial-lysine-transport Reconstituted human SLC25A29 transports lysine by uniport and exchange, supporting lysine entry into the mitochondrial matrix. Plain language: SLC25A29 gives lysine access to mitochondrial metabolism. Condition category: normal organism: Homo sapiens tissue_or_cell_type: Inner mitochondrial membrane experimental_model: Purified recombinant carrier reconstituted in liposomes limitations: Physiological import role is inferred from transport properties and localization; not a carnitine transporter. [porcelli2014] The Human Gene SLC25A29, of Solute Carrier Family 25, Encodes a Mitochondrial Transporter of Basic Amino Acids (2014). https://pmc.ncbi.nlm.nih.gov/articles/PMC4036346/ DOI: 10.1074/jbc.M114.547448
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.