Component
SARS-CoV-2 viral RNA in Vero-hSLAM culture
Viral RNA measured in a monkey kidney cell line.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
A single addition of ivermectin to SARS-CoV-2-infected Vero-hSLAM cells two hours after infection produced approximately a five thousand fold reduction in viral RNA at forty-eight hours.
Experimental context and source evidence
- duration
- 48 hours
- evidence_access
- Primary PubMed abstract and indexed metadata reviewed. Full-text method details not stated here remain unresolved.
- experimental_model
- Vero-hSLAM cell culture
- exposure
- Single ivermectin addition two hours post infection
- limitations
- This is a cell-culture result in a monkey kidney line, and the authors state only that it warrants further investigation for possible benefits in humans. The concentration relationship to human plasma exposure is not addressed in the report and remains unresolved here.
- organism
- Vero-hSLAM cell culture
- plain_language
- A single addition of ivermectin to SARS-CoV-2-infected Vero-hSLAM cells two hours after infection produced approximately a five thousand fold reduction in viral RNA at forty-eight hours.
- primary_references
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. (2020). https://pubmed.ncbi.nlm.nih.gov/32251768/ DOI: 10.1016/j.antiviral.2020.104787
- route
- In vitro
- tissue
- Viral RNA
Ivermectin: mechanism of action across parasite, host barrier and mammalian targets (2026-09-22) · lines 167–176
Original AI-assisted curation of sixteen primary studies resolved by PubMed title search and cross-checked against live PubMed metadata. Study-specific citations, concentrations, negative findings and limitations retained. Not publisher full text. · supports · · source_derived_draft · unverified_draft
## ivermectin-sars-cov-2-cell-culture A single addition of ivermectin to SARS-CoV-2-infected Vero-hSLAM cells two hours after infection produced approximately a five thousand fold reduction in viral RNA at forty-eight hours. Model/species: Vero-hSLAM cell culture Tissue/system: Viral RNA Exposure: Single ivermectin addition two hours post infection Route: In vitro Duration: 48 hours Limits: This is a cell-culture result in a monkey kidney line, and the authors state only that it warrants further investigation for possible benefits in humans. The concentration relationship to human plasma exposure is not addressed in the report and remains unresolved here. Primary reference: The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. (2020). https://pubmed.ncbi.nlm.nih.gov/32251768/ DOI: 10.1016/j.antiviral.2020.104787 Access: Primary PubMed abstract and indexed metadata reviewed. Full-text method details not stated here remain unresolved.
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.