Component

Rhamnogalacturonan-I-derived oligosaccharides

Rhamnogalacturonan-I-derived oligosaccharides. Species, exposure and limitations are retained in each linked claim.

6 recorded relationships. Experimental role, claim status and evidence remain attached to each record.

Read recorded mechanisms Open recursive mind map

How nutrients influence it

Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.

How nutrients reach it in more than one step

Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.

Tracing routes…

What it does

Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.

Recorded relationships

What acts on it

  1. BT4176 removes unsaturated terminal residues from RG-I fragments of degree of polymerization two.

    Bacteroides thetaiotaomicron BT4176, unsaturated RG-I hydrolase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    Very short RG-I fragments use a particular enzyme.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 178–189

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-dimer BT4176 removes unsaturated terminal residues from RG-I fragments of degree of polymerization two. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Very short RG-I fragments use a particular enzyme. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

  2. BT4146 targets the tested GalA-Rha backbone substrate at degree of polymerization two.

    Bacteroides thetaiotaomicron BT4146, GH28 rhamnogalacturonidase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    One galacturonidase specializes in the shortest tested fragments.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 217–228

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-gala2 BT4146 targets the tested GalA-Rha backbone substrate at degree of polymerization two. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: One galacturonidase specializes in the shortest tested fragments. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

  3. BT4153 targets the tested GalA-Rha backbone substrates with degree of polymerization at least two.

    Bacteroides thetaiotaomicron BT4153, GH28 rhamnogalacturonidase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    A related enzyme accepts a broader fragment-length range.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 230–241

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-gala2plus BT4153 targets the tested GalA-Rha backbone substrates with degree of polymerization at least two. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A related enzyme accepts a broader fragment-length range. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

  4. BT4149 targets the tested GalA-Rha backbone substrates with degree of polymerization at least four.

    Bacteroides thetaiotaomicron BT4149, GH28 rhamnogalacturonidase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    A third enzyme processes longer fragments.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 243–254

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-gala4plus BT4149 targets the tested GalA-Rha backbone substrates with degree of polymerization at least four. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: A third enzyme processes longer fragments. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

  5. BT4174 processes the unsaturated terminal residue in RG-I fragments of degree of polymerization at least four.

    Bacteroides thetaiotaomicron BT4174, unsaturated RG-I hydrolase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    Longer fragments use a different enzyme.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 191–202

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-long BT4174 processes the unsaturated terminal residue in RG-I fragments of degree of polymerization at least four. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: Longer fragments use a different enzyme. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

  6. BT4145 is an RG-I-specific GH106 alpha-L-rhamnosidase acting by inversion.

    Bacteroides thetaiotaomicron BT4145, GH106 alpha-rhamnosidase → Rhamnogalacturonan-I-derived oligosaccharides source_derived_draftungraded
    Experimental context and source evidence
    evidence_span
    {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"}
    experimental_model
    Purified enzymes, structural biology and targeted bacterial deletions
    exposure
    Defined pectic substrates; growth media and recombinant-enzyme assays
    limitations
    Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows.
    nutrient_topic
    Pectin research collection; topical membership is not evidence of a direct dietary effect. · Pectin, structurally heterogeneous plant polysaccharides
    organism
    Bacteroides thetaiotaomicron
    plain_language
    This enzyme removes rhamnose links in the RG-I sequence.
    primary_references
    [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    tissue_or_cell_type
    Cell surface and periplasm

    Pectin: metabolism, signaling and nutrient connections (2026-09-17) · lines 204–215

    AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified enzymes, structural biology and targeted bacterial deletions · source_derived_draft · unverified_draft

    ### pectin-rgi-rhamnose BT4145 is an RG-I-specific GH106 alpha-L-rhamnosidase acting by inversion. Condition category: normal nutrient_topic: Pectin research collection; topical membership is not evidence of a direct dietary effect. plain_language: This enzyme removes rhamnose links in the RG-I sequence. organism: Bacteroides thetaiotaomicron tissue_or_cell_type: Cell surface and periplasm experimental_model: Purified enzymes, structural biology and targeted bacterial deletions limitations: Bacterial machinery, not human digestive enzymes. Gene dependence is substrate- and strain-specific; no clinical microbiome threshold follows. exposure: Defined pectic substrates; growth media and recombinant-enzyme assays evidence_span: {"source_cache": "artifacts/pectin-research/29255254.fulltext.txt", "locator": "Primary full-text span; zero-based, end-exclusive Unicode character offsets", "file_sha256": "514f1ffe2924a1c555e3ecea968fb7260d0f55aa1b22c057697dbc59676c5796", "start_char": 13259, "end_char": 14426, "text_sha256": "2e55a6b2c9c29b9f82f572f66f439f63e58c9619942be2ed1b35ee8e7a193938"} [pectin-p29255254] Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. (2018). https://pubmed.ncbi.nlm.nih.gov/29255254/ DOI: 10.1038/s41564-017-0079-1
    Complete structured claim and evidence

In the sources

Preserved passages that mention this component, quoted exactly. Open one to read it in context.

    This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.

    Evidence, AI assistance and curation standards