Component
Rat mitochondrial uncoupling protein 1 / Ucp1
Rat mitochondrial uncoupling protein 1 / Ucp1. Species, exposure and limitations are retained in each linked claim.
1 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
The aqueous extract increased UCP1 expression in the treated diabetic-rat tissue study.
Experimental context and source evidence
- evidence_span
- {"source_cache": "artifacts/ceylon-research/21150113.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3a58afe3cd3cd503ea2fba0faeb90aee891bceab69a523e3a8c1de27ed9c04d9", "start_char": 0, "end_char": 1075, "text_sha256": "3a58afe3cd3cd503ea2fba0faeb90aee891bceab69a523e3a8c1de27ed9c04d9"}
- experimental_model
- STZ-diabetic rat treatment and mouse adipocyte experiments
- exposure
- Aqueous extract for 22 days in rats; effects reported above 30 mg/kg/day
- limitations
- Extract effects cannot be assigned to pure cinnamaldehyde or substituted for insulin in humans.
- nutrient_topic
- Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. · Ceylon cinnamon / Cinnamomum verum bark preparations
- organism
- Rat
- plain_language
- The rat energy-handling machinery changed.
- primary_references
- [ceylon-p21150113] Verification of the antidiabetic effects of cinnamon (Cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. (2010). https://pubmed.ncbi.nlm.nih.gov/21150113/ DOI: 10.1271/bbb.100453
- tissue_or_cell_type
- Brown adipose tissue and muscle
Ceylon cinnamon: metabolism, signaling and nutrient connections (2026-09-17) · lines 467–478
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · STZ-diabetic rat treatment and mouse adipocyte experiments · source_derived_draft · unverified_draft
### ceylon-rat-ucp1 The aqueous extract increased UCP1 expression in the treated diabetic-rat tissue study. Condition category: normal nutrient_topic: Ceylon cinnamon research collection; topical membership is not evidence of a direct dietary effect. plain_language: The rat energy-handling machinery changed. organism: Rat tissue_or_cell_type: Brown adipose tissue and muscle experimental_model: STZ-diabetic rat treatment and mouse adipocyte experiments limitations: Extract effects cannot be assigned to pure cinnamaldehyde or substituted for insulin in humans. exposure: Aqueous extract for 22 days in rats; effects reported above 30 mg/kg/day evidence_span: {"source_cache": "artifacts/ceylon-research/21150113.abstract.txt", "locator": "Primary indexed abstract; zero-based, end-exclusive Unicode character offsets", "file_sha256": "3a58afe3cd3cd503ea2fba0faeb90aee891bceab69a523e3a8c1de27ed9c04d9", "start_char": 0, "end_char": 1075, "text_sha256": "3a58afe3cd3cd503ea2fba0faeb90aee891bceab69a523e3a8c1de27ed9c04d9"} [ceylon-p21150113] Verification of the antidiabetic effects of cinnamon (Cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. (2010). https://pubmed.ncbi.nlm.nih.gov/21150113/ DOI: 10.1271/bbb.100453
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.