Component
Rat alpha-tocopherol transfer protein
Rattus norvegicus alpha-TTP purified from liver in Hosomi 1997.
3 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What it acts on
In a rat alpha-TTP membrane-transfer competition assay, alpha-tocotrienol had relative affinity 12.4% of RRR-alpha-tocopherol (100%).
Experimental context and source evidence
- cross_nutrient
- false
- experimental_model
- Purified rat liver protein and membrane-transfer competition
- exposure
- 37 °C, 30 min; Table 1 competition-derived affinity.
- limitations
- Relative transfer competition, not a direct Kd or human clinical efficacy ratio.
- nutrient_topic
- Vitamin E research collection; topical membership is not evidence of a direct dietary effect. · Vitamin E
- organism
- Rattus norvegicus
- plain_language
- Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol.
- primary_references
- [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
- tissue_or_cell_type
- Liver protein/liposomes
Vitamin E: transport, membrane protection and nutrient interactions (2026-09-17) · lines 168–179
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified rat liver protein and membrane-transfer competition · source_derived_draft · unverified_draft
### ve-transport-rat-ttp-affinity-alpha-tocotrienol In a rat alpha-TTP membrane-transfer competition assay, alpha-tocotrienol had relative affinity 12.4% of RRR-alpha-tocopherol (100%). Condition category: normal nutrient_topic: Vitamin E research collection; topical membership is not evidence of a direct dietary effect. plain_language: Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol. organism: Rattus norvegicus tissue_or_cell_type: Liver protein/liposomes experimental_model: Purified rat liver protein and membrane-transfer competition limitations: Relative transfer competition, not a direct Kd or human clinical efficacy ratio. exposure: 37 °C, 30 min; Table 1 competition-derived affinity. cross_nutrient: false [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
Complete structured claim and evidenceIn a rat alpha-TTP membrane-transfer competition assay, gamma-tocopherol had relative affinity 8.9% of RRR-alpha-tocopherol (100%).
Experimental context and source evidence
- cross_nutrient
- false
- experimental_model
- Purified rat liver protein and membrane-transfer competition
- exposure
- 37 °C, 30 min; Table 1 competition-derived affinity.
- limitations
- Relative transfer competition, not a direct Kd or human clinical efficacy ratio.
- nutrient_topic
- Vitamin E research collection; topical membership is not evidence of a direct dietary effect. · Vitamin E
- organism
- Rattus norvegicus
- plain_language
- Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol.
- primary_references
- [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
- tissue_or_cell_type
- Liver protein/liposomes
Vitamin E: transport, membrane protection and nutrient interactions (2026-09-17) · lines 155–166
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified rat liver protein and membrane-transfer competition · source_derived_draft · unverified_draft
### ve-transport-rat-ttp-affinity-gamma-tocopherol In a rat alpha-TTP membrane-transfer competition assay, gamma-tocopherol had relative affinity 8.9% of RRR-alpha-tocopherol (100%). Condition category: normal nutrient_topic: Vitamin E research collection; topical membership is not evidence of a direct dietary effect. plain_language: Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol. organism: Rattus norvegicus tissue_or_cell_type: Liver protein/liposomes experimental_model: Purified rat liver protein and membrane-transfer competition limitations: Relative transfer competition, not a direct Kd or human clinical efficacy ratio. exposure: 37 °C, 30 min; Table 1 competition-derived affinity. cross_nutrient: false [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
Complete structured claim and evidenceIn a rat alpha-TTP membrane-transfer competition assay, SRR-alpha-tocopherol had relative affinity 10.5% of RRR-alpha-tocopherol (100%).
Experimental context and source evidence
- cross_nutrient
- false
- experimental_model
- Purified rat liver protein and membrane-transfer competition
- exposure
- 37 °C, 30 min; Table 1 competition-derived affinity.
- limitations
- Relative transfer competition, not a direct Kd or human clinical efficacy ratio.
- nutrient_topic
- Vitamin E research collection; topical membership is not evidence of a direct dietary effect. · Vitamin E
- organism
- Rattus norvegicus
- plain_language
- Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol.
- primary_references
- [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
- tissue_or_cell_type
- Liver protein/liposomes
Vitamin E: transport, membrane protection and nutrient interactions (2026-09-17) · lines 142–153
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Purified rat liver protein and membrane-transfer competition · source_derived_draft · unverified_draft
### ve-transport-rat-ttp-affinity-srr-alpha-tocopherol In a rat alpha-TTP membrane-transfer competition assay, SRR-alpha-tocopherol had relative affinity 10.5% of RRR-alpha-tocopherol (100%). Condition category: normal nutrient_topic: Vitamin E research collection; topical membership is not evidence of a direct dietary effect. plain_language: Rat alpha-TTP distinguished this form from RRR-alpha-tocopherol. organism: Rattus norvegicus tissue_or_cell_type: Liver protein/liposomes experimental_model: Purified rat liver protein and membrane-transfer competition limitations: Relative transfer competition, not a direct Kd or human clinical efficacy ratio. exposure: 37 °C, 30 min; Table 1 competition-derived affinity. cross_nutrient: false [hosomi1997] Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. (1997). https://pubmed.ncbi.nlm.nih.gov/9199513/ DOI: 10.1016/s0014-5793(97)00499-7
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.