Component
Rabbit skeletal-muscle glycogen phosphorylase
Rabbit skeletal-muscle glycogen phosphorylase
2 recorded relationships. Experimental role, claim status and evidence remain attached to each record.
How nutrients influence it
Every nutrient with a recorded effect on this component, credited to the nutrient that acted rather than the chapter that recorded it. Open a nutrient to see the findings and the conditions they were measured under.
Other things that act on it
Enzymes, hormones, genes, and other components with a recorded effect. These are not nutrients, so they do not count toward the arrows above. Each finding names the chapter that recorded it.
How nutrients reach it in more than one step
Chains of two or more recorded steps that end here, grouped by the nutrient they start from. Each step is a separate finding, so a chain is a route a mechanism could take, not proof that it does.
Tracing routes…
What it does
Every recorded relationship this component is part of, grouped by its role. Plain wording comes first; the technical statement follows.
What acts on it
A labeled cofactor-analogue experiment supported direct participation of the PLP phosphate group in glycogen phosphorylase glucosyl transfer.
Experimental context and source evidence
- cross_nutrient
- PLP-phosphate chemistry supports glycogen metabolism.
- experimental_model
- Rabbit muscle phosphorylase reconstituted with synthetic cofactor analogue
- exposure
- Synthetic pyridoxal-diphospho-glucose analogue reconstitution
- limitations
- Mechanistic analogue evidence; not a demonstration of muscle glycogen failure in human B6 deficiency.
- nutrient_topic
- Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. · Vitamin B6
- organism
- Oryctolagus cuniculus
- plain_language
- The phosphate portion of active B6 helps this carbohydrate reaction.
- primary_references
- [b6-phosphorylase-1982] Catalytic mechanism of glycogen phosphorylase: pyridoxal(5')diphospho(1)-alpha-D-glucose as a transition-state analogue. (1982). https://pmc.ncbi.nlm.nih.gov/articles/PMC346497/ DOI: 10.1073/pnas.79.12.3716
- tissue_or_cell_type
- Rabbit skeletal-muscle protein
Vitamin B6: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 860–871
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Rabbit muscle phosphorylase reconstituted with synthetic cofactor analogue · source_derived_draft · unverified_draft
### b6-met-rabbit-phosphorylase-phosphate A labeled cofactor-analogue experiment supported direct participation of the PLP phosphate group in glycogen phosphorylase glucosyl transfer. Condition category: normal nutrient_topic: Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. plain_language: The phosphate portion of active B6 helps this carbohydrate reaction. organism: Oryctolagus cuniculus tissue_or_cell_type: Rabbit skeletal-muscle protein experimental_model: Rabbit muscle phosphorylase reconstituted with synthetic cofactor analogue limitations: Mechanistic analogue evidence; not a demonstration of muscle glycogen failure in human B6 deficiency. cross_nutrient: PLP-phosphate chemistry supports glycogen metabolism. exposure: Synthetic pyridoxal-diphospho-glucose analogue reconstitution [b6-phosphorylase-1982] Catalytic mechanism of glycogen phosphorylase: pyridoxal(5')diphospho(1)-alpha-D-glucose as a transition-state analogue. (1982). https://pmc.ncbi.nlm.nih.gov/articles/PMC346497/ DOI: 10.1073/pnas.79.12.3716
Complete structured claim and evidenceRabbit muscle phosphorylase crystallography located PLP buried next to the catalytic glucose-binding site.
Experimental context and source evidence
- cross_nutrient
- B6-linked glycogen chemistry involves phosphate-containing substrates.
- experimental_model
- Rabbit skeletal muscle glycogen phosphorylase crystallography
- limitations
- Rabbit structure; the spatial relationship alone does not establish every catalytic step.
- nutrient_topic
- Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. · Vitamin B6
- organism
- Oryctolagus cuniculus
- plain_language
- B6 also participates in glycogen metabolism.
- primary_references
- [b6-phosphorylase-1977] Location of pyridoxal phosphate in glycogen phosphorylase a. (1977). https://pmc.ncbi.nlm.nih.gov/articles/PMC432034/ DOI: 10.1073/pnas.74.11.4757
- tissue_or_cell_type
- Rabbit skeletal-muscle protein
Vitamin B6: mechanisms, deficiency and nutrient interactions (2026-09-17) · lines 848–858
AI-assisted literature curation; primary study URLs and scope retained in the document and extraction. Not publisher full text. · supports · Rabbit skeletal muscle glycogen phosphorylase crystallography · source_derived_draft · unverified_draft
### b6-met-rabbit-phosphorylase-plp Rabbit muscle phosphorylase crystallography located PLP buried next to the catalytic glucose-binding site. Condition category: normal nutrient_topic: Vitamin B6 research collection; topical membership is not evidence of a direct dietary effect. plain_language: B6 also participates in glycogen metabolism. organism: Oryctolagus cuniculus tissue_or_cell_type: Rabbit skeletal-muscle protein experimental_model: Rabbit skeletal muscle glycogen phosphorylase crystallography limitations: Rabbit structure; the spatial relationship alone does not establish every catalytic step. cross_nutrient: B6-linked glycogen chemistry involves phosphate-containing substrates. [b6-phosphorylase-1977] Location of pyridoxal phosphate in glycogen phosphorylase a. (1977). https://pmc.ncbi.nlm.nih.gov/articles/PMC432034/ DOI: 10.1073/pnas.74.11.4757
Complete structured claim and evidence
The events it takes part in
A mechanism often involves more than two components. These are the full events, with every participant and its role.
Situations it appears in
Low-supply and faulty-machinery situations recorded in the chapters where this component plays a part.
In the sources
Preserved passages that mention this component, quoted exactly. Open one to read it in context.
Open hypotheses
Proposed ideas that involve this component. They are labeled as hypotheses and do not change any recorded statement.
This is a research prototype built from draft material. It is not medical advice, and its statements still await verification against the original studies.